Tazeoglu Deniz, Esmer Ahmet Cem, Arslan Bilal, Dag Ahmet
General Surgery, Faculty of Medicine Mersin University, Mersin, TUR.
Cureus. 2022 Apr 30;14(4):e24631. doi: 10.7759/cureus.24631. eCollection 2022 Apr.
Background The coronavirus disease 2019 (COVID-19) pandemic has changed the lives and habits of people all over the world. In this study, it was planned to investigate the effect of the COVID-19 pandemic on the diagnosis and treatment duration of acute appendicitis (AA), morbidity and mortality. Methods The data of patients who were operated on with the diagnosis of AA in our clinic between March 2019 and March 2021, divided into pre-COVID and post-COVID periods, were analyzed. Patients diagnosed with AA, who had the only appendectomy perioperatively, and who had complete preoperative blood analysis and radiological imaging data were included in the study. Results The time from the onset of symptoms to the time of admission to the hospital was statistically significantly longer than in the post-COVID group (p=0.04). During the COVID-19 pandemic period, the use of ultrasonography was statistically significantly reduced (p<0.01); computed tomography use increased (p<0.001). Laparoscopic appendectomy as a surgical technique decreased statistically significantly during the pandemic period (p=0.02). Postoperative complications and the postoperative complication severity degrees were not statistically significant between periods (p=0.24, p=0.68). The risk for the occurrence of postoperative complications in COVID-19 positive patients was statistically higher (p=0.01) (OR: 9.38 95% CI: 1.96 - 44.88). Conclusion The COVID-19 pandemic had caused delays in the admission and diagnosis of patients who might need surgery due to AA. Postoperative complication frequency and complication severity classification were not affected. COVID-19 positivity was a risk factor for complex AA presenting with periappendicular abscess, gangrenous and perforated appendix.
背景 2019 冠状病毒病(COVID-19)大流行改变了全世界人们的生活和习惯。本研究旨在调查 COVID-19 大流行对急性阑尾炎(AA)的诊断和治疗时长、发病率及死亡率的影响。方法 分析 2019 年 3 月至 2021 年 3 月期间在我院因 AA 诊断而接受手术的患者数据,分为 COVID 之前和之后两个时期。纳入研究的患者为诊断为 AA、围手术期仅接受阑尾切除术、术前血液分析和放射影像数据完整的患者。结果 症状出现至入院的时间在统计学上显著长于 COVID 之后组(p = 0.04)。在 COVID-19 大流行期间,超声检查的使用在统计学上显著减少(p < 0.01);计算机断层扫描的使用增加(p < 0.001)。作为一种手术技术,腹腔镜阑尾切除术在大流行期间在统计学上显著减少(p = 0.02)。各时期之间术后并发症及术后并发症严重程度无统计学意义(p = 0.24,p = 0.68)。COVID-19 阳性患者术后发生并发症的风险在统计学上更高(p = 0.01)(比值比:9.38,95%可信区间:1.96 - 44.88)。结论 COVID-19 大流行导致因 AA 可能需要手术的患者入院和诊断延迟。术后并发症发生率和并发症严重程度分级未受影响。COVID-19 阳性是伴有阑尾周围脓肿、坏疽性和穿孔性阑尾炎的复杂性 AA 的一个危险因素。