Janz S, Püschel W, Raabe F, Storch H
Arch Geschwulstforsch. 1987;57(1):25-30.
Plasmacytomas were readily induced in BALB/c mice by three bimonthly i.p. injections of 0.5 ml pristane or paraffin oil. Additionally, two groups of mice were simultaneously given a prolonged antigenic stimulation with bovine serum albumin (BSA). The tumour incidence found in mice treated with pristane and BSA (75%) was higher than the plasmacytoma incidence in mice subjected to paraffin oil and BSA inoculations (53.7%, p = 0.05). The sustained antigenic stimulation with BSA had no effect on cumulative plasmacytoma incidence.
通过每两个月腹腔注射0.5毫升 pristane或石蜡油，可在BALB/c小鼠中轻易诱发浆细胞瘤。此外，两组小鼠同时接受了牛血清白蛋白（BSA）的长期抗原刺激。接受pristane和BSA治疗的小鼠的肿瘤发生率（75%）高于接受石蜡油和BSA接种的小鼠的浆细胞瘤发生率（53.7%，p = 0.05）。用BSA进行的持续抗原刺激对累积浆细胞瘤发生率没有影响。
