在注射矿物油的小鼠中，内毒素对浆细胞瘤发展的增强作用。
Endotoxin enhancement of plasma cell tumor development in mice given injections of mineral oil.
作者信息
Bober L A, Kranepool M J, Bojko C, Steiner G, Hollander V P
出版信息
Cancer Res. 1976 Jun;36(6):1947-9.
PMID:773532
Abstract
Bacterial endotoxins administered to BALB/c mice given i.p. mineral oil cause an increased incidence of plasma cell tumors, compared with mice given either oil or antigens alone, or oil plus antigen other than endotoxin. Endotoxin in ng doses was more effective than in mug doses.
摘要
与单独给予矿物油、抗原或给予除内毒素外的油加抗原的小鼠相比，腹腔注射矿物油的BALB/c小鼠给予细菌内毒素会导致浆细胞瘤发病率增加。纳克剂量的内毒素比微克剂量的更有效。
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