Shliapnikov V V
Arkh Patol. 1986;48(12):53-7.
112 cases of renal cell carcinoma were studied histologically and histochemically. Variants of renal cell carcinoma were found to have certain histochemical peculiarities: accumulation of neutral fat and cholesterol esters in the clear-cell tumor variant and bound lipids and proteins in the tumors of granular cell, sarcoma-like and glandular variants. These characteristics become less distinct with decrease of differentiation degree of tumor cells. These features can be used for differential diagnosis of renal cell carcinoma.
对112例肾细胞癌进行了组织学和组织化学研究。发现肾细胞癌的不同变体具有某些组织化学特性:透明细胞肿瘤变体中中性脂肪和胆固醇酯的积累,以及颗粒细胞、肉瘤样和腺性变体肿瘤中结合脂质和蛋白质的积累。随着肿瘤细胞分化程度的降低,这些特征变得不那么明显。这些特征可用于肾细胞癌的鉴别诊断。