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单独灌肠与灌肠联合口服聚乙二醇在老年患者经阴道盆底重建术前肠道准备中的对比评价:一项回顾性队列研究。

Comparative evaluation of enema alone and in combination with oral polyethylene glycol for bowel preparation before transvaginal pelvic floor reconstruction in elderly patients: a retrospective cohort study.

机构信息

Department of Gynecology and Obstetrics, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.

出版信息

J Obstet Gynaecol. 2022 Aug;42(6):2406-2410. doi: 10.1080/01443615.2022.2069002. Epub 2022 Jun 6.

DOI:10.1080/01443615.2022.2069002
PMID:35666941
Abstract

The aim of this retrospective study was to assess the value of using an enema alone for mechanical bowel preparation (MBP) before transvaginal pelvic floor reconstruction (TPFR) in patients ≥65 years old. In total, 190 patients were included [81 in the enema group 109 in the enema + polyethylene glycol (PEG) group]. The levels of serum potassium ( = .004) and calcium ( = .005) were higher in the enema group after surgery. The decrease in serum calcium was more significant in the enema + PEG group ( = .027). More patients in the enema + PEG group developed hypokalaemia ( = .035) or hypocalcaemia ( = .008) after surgery. The incidence of thrombus and surgical site infection was similar and earlier bowel movement was evident in the enema group ( = .000). Overall, the enema group used more laxatives ( = .026). Using enema alone before TPFR reduces the incidence of electrolyte disturbances with no increase in surgical complications in elderly patients.IMPACT STATEMENT TPFR is an effective treatment for pelvic organ prolapse (POP) in elderly women. Bowel preparation performed before gynecological surgery can reduce surgical site infection, but increase discomfort and electrolyte disturbance. The levels of serum potassium and calcium were lower in the enema + PEG group than in the enema group after surgery and more patients developed hypokalaemia or hypocalcaemia in the enema + PEG group. The incidence of thrombus and surgical site infection was similar between the two groups. Bowel movement was earlier in the enema group. Using enema alone before TPFR reduces the incidence of electrolyte disturbance and does not increase surgical complications. This conclusion needs to be confirmed by random controlled trial studies in the future.

摘要

本回顾性研究旨在评估在≥65 岁的经阴道盆底重建术(TPFR)患者中单独使用灌肠作为机械肠道准备(MBP)的价值。共纳入 190 例患者[灌肠组 81 例,灌肠+聚乙二醇(PEG)组 109 例]。术后灌肠组血清钾( = .004)和钙( = .005)水平升高。灌肠+PEG 组血清钙下降更显著( = .027)。术后灌肠+PEG 组低钾血症( = .035)或低钙血症( = .008)发生率更高。两组血栓和手术部位感染发生率相似,灌肠组肠蠕动更早( = .000)。总体而言,灌肠+PEG 组泻药使用更多( = .026)。在 TPFR 前单独使用灌肠可减少电解质紊乱的发生率,且不会增加老年患者的手术并发症。

TPFR 是治疗老年女性盆腔器官脱垂(POP)的有效方法。妇科手术前进行肠道准备可以降低手术部位感染的风险,但会增加不适感和电解质紊乱。术后灌肠+PEG 组血清钾和钙水平低于灌肠组,且灌肠+PEG 组低钾血症或低钙血症发生率更高。两组血栓和手术部位感染发生率相似。灌肠组肠蠕动更早。在 TPFR 前单独使用灌肠可减少电解质紊乱的发生率,且不会增加手术并发症。这一结论需要未来的随机对照试验研究加以证实。

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