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终末期肺动脉高压患者的连续心脏监测及最终的双侧肺移植。

Continuous cardiac monitoring in a patient with terminal pulmonary hypertension and eventual bilateral lung transplantation.

机构信息

Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

出版信息

BMJ Case Rep. 2022 Jun 6;15(6):e248304. doi: 10.1136/bcr-2021-248304.

Abstract

As pulmonary arterial hypertension (PAH) progress, arrhythmias are becoming an increasingly prominent phenomenon. Supraventricular tachycardias have been shown to have an incidence of up to 35% in pulmonary hypertension.Continuous cardiac monitoring was deployed in a patient with severe PAH 100 days before bilateral lung transplantation (BLTX). Despite being graded as WHO functional class IV, no arrhythmias were observed before BLTX. Furthermore, the case describes clinical improvement, along with a significant increase in heart rate variability (HRV) and decrease in night-time heart rate in the post-transplantation period.No arrhythmias were observed preoperatively during continuous monitoring in a 100-day period despite the patient's intrinsically high risk for arrhythmias. Increasing HRV and lower resting heart rate were observed after BLTX. Since these parameters correlate with the clinical condition, they might be valuable in risk assessment in patients with pulmonary hypertension.

摘要

随着肺动脉高压(PAH)的进展,心律失常现象变得越来越突出。已表明,在肺动脉高压中,室上性心动过速的发生率高达 35%。在双侧肺移植(BLTX)前 100 天,对一名患有严重 PAH 的患者部署了连续心脏监测。尽管被评为世界卫生组织功能分级 IV,但在 BLTX 前没有观察到心律失常。此外,该病例描述了临床改善,以及在移植后期间心率变异性(HRV)显著增加和夜间心率降低。尽管患者本身存在心律失常的高风险,但在连续监测的 100 天内,术前未观察到心律失常。BLTX 后,HRV 增加,静息心率降低。由于这些参数与临床状况相关,因此它们可能对肺动脉高压患者的风险评估有价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de44/9171191/093daffcaf4b/bcr-2021-248304f01.jpg

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