• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

使用β-胡萝卜素预防和治疗疾病:终极维生素A原

Disease Prevention and Treatment Using β-Carotene: the Ultimate Provitamin A.

作者信息

Anand Raksha, Mohan Lalit, Bharadvaja Navneeta

机构信息

Plant Biotechnology Laboratory, Department of Biotechnology, Delhi Technological University, Delhi, India.

出版信息

Rev Bras Farmacogn. 2022;32(4):491-501. doi: 10.1007/s43450-022-00262-w. Epub 2022 May 30.

DOI:10.1007/s43450-022-00262-w
PMID:35669276
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9150880/
Abstract

Humans being unable to synthesize beta-carotene, the provitamin A, depend on external sources as its supplement. Health benefits and dietary requirements of beta-carotene are interrelated. This orange-red coloured pigment has been enormously examined for its capacity to alleviate several chronic diseases including various types of cancer, cystic fibrosis, as well as COVID-19. However, this class of phytoconstituents has witnessed a broad research gap due to several twin conclusions that have been reported. Natural sources for these compounds along with their extraction methods have been mentioned. The current communication aims at contributing to the global scientific literature on beta-carotene's application in prevention and treatment of lifestyle diseases.

摘要

人类无法合成维生素A原β-胡萝卜素,因此依赖外部来源作为补充。β-胡萝卜素的健康益处和饮食需求是相互关联的。这种橙红色色素因其缓解多种慢性疾病的能力而受到大量研究,这些疾病包括各类癌症、囊性纤维化以及新冠肺炎。然而,由于已报道的一些相互矛盾的结论,这类植物成分存在广泛的研究空白。文中提到了这些化合物的天然来源及其提取方法。本通讯旨在为全球科学文献贡献关于β-胡萝卜素在预防和治疗生活方式疾病方面应用的内容。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28bd/9150880/995246fb26a8/43450_2022_262_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28bd/9150880/bc5836e17959/43450_2022_262_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28bd/9150880/107678586885/43450_2022_262_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28bd/9150880/19d49cd9e3e1/43450_2022_262_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28bd/9150880/9032b181f217/43450_2022_262_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28bd/9150880/995246fb26a8/43450_2022_262_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28bd/9150880/bc5836e17959/43450_2022_262_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28bd/9150880/107678586885/43450_2022_262_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28bd/9150880/19d49cd9e3e1/43450_2022_262_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28bd/9150880/9032b181f217/43450_2022_262_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28bd/9150880/995246fb26a8/43450_2022_262_Fig5_HTML.jpg

相似文献

1
Disease Prevention and Treatment Using β-Carotene: the Ultimate Provitamin A.使用β-胡萝卜素预防和治疗疾病:终极维生素A原
Rev Bras Farmacogn. 2022;32(4):491-501. doi: 10.1007/s43450-022-00262-w. Epub 2022 May 30.
2
Assessment of dietary vitamin A intake (retinol, α-carotene, β-carotene, β-cryptoxanthin) and its sources in the National Survey of Dietary Intake in Spain (2009-2010).西班牙膳食摄入量全国调查(2009 - 2010年)中膳食维生素A摄入量(视黄醇、α-胡萝卜素、β-胡萝卜素、β-隐黄质)及其来源的评估。
Int J Food Sci Nutr. 2015;66(6):706-12. doi: 10.3109/09637486.2015.1077787. Epub 2015 Aug 27.
3
Beta carotene: from biochemistry to clinical trials.β-胡萝卜素:从生物化学到临床试验
Nutr Rev. 2000 Feb;58(2 Pt 1):39-53. doi: 10.1111/j.1753-4887.2000.tb07810.x.
4
[Progress in metabolic engineering of β-carotene synthesis].[β-胡萝卜素合成的代谢工程进展]
Sheng Wu Gong Cheng Xue Bao. 2017 Apr 25;33(4):578-590. doi: 10.13345/j.cjb.160356.
5
Beta-carotene's effects on serum lipoproteins and immunologic indices in humans.β-胡萝卜素对人体血清脂蛋白和免疫指标的影响。
Am J Clin Nutr. 1991 Mar;53(3):688-94. doi: 10.1093/ajcn/53.3.688.
6
Oxidized β-Carotene Is a Novel Phytochemical Immune Modulator That Supports Animal Health and Performance for Antibiotic-Free Production.氧化β-胡萝卜素是一种新型植物化学免疫调节剂,可支持动物健康并提高无抗生素生产的性能。
Animals (Basel). 2023 Jan 14;13(2):289. doi: 10.3390/ani13020289.
7
Provitamin A-biofortified maize consumption increases serum xanthophylls and C-natural abundance of retinol in Zambian children.食用富含维生素A原的生物强化玉米可增加赞比亚儿童血清叶黄素和视黄醇的碳自然丰度。
Exp Biol Med (Maywood). 2017 Sep;242(15):1508-1514. doi: 10.1177/1535370217728500. Epub 2017 Aug 24.
8
The importance of beta-carotene as a source of vitamin A with special regard to pregnant and breastfeeding women.β-胡萝卜素作为维生素A来源的重要性,尤其针对孕妇和哺乳期妇女。
Eur J Nutr. 2007 Jul;46 Suppl 1:I1-20. doi: 10.1007/s00394-007-1001-z.
9
Antioxidant β-carotene does not quench singlet oxygen in mammalian cells.抗氧化剂β-胡萝卜素不能淬灭哺乳动物细胞中的单线态氧。
J Am Chem Soc. 2013 Jan 9;135(1):272-9. doi: 10.1021/ja308930a. Epub 2012 Dec 28.
10
The Extraction of β-Carotene from Microalgae for Testing Their Health Benefits.从微藻中提取β-胡萝卜素以测试其健康益处。
Foods. 2022 Feb 10;11(4):502. doi: 10.3390/foods11040502.

引用本文的文献

1
Development of a New Tomato Sauce Enriched with Bioactive Compounds Through the Use of Processing By-Products and Vegetables.通过利用加工副产物和蔬菜开发富含生物活性化合物的新型番茄酱。
Foods. 2025 Jun 9;14(12):2037. doi: 10.3390/foods14122037.
2
The relationship between the composite dietary antioxidant index and rheumatoid arthritis risk in American adults: the mediating role of BMI.美国成年人复合膳食抗氧化指数与类风湿关节炎风险之间的关系:BMI的中介作用。
Front Immunol. 2025 Apr 9;16:1560570. doi: 10.3389/fimmu.2025.1560570. eCollection 2025.
3
Advancements and challenges in microalgal protein production: A sustainable alternative to conventional protein sources.

本文引用的文献

1
β-Carotene Supplementation and Risk of Cardiovascular Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.β-胡萝卜素补充剂与心血管疾病风险:随机对照试验的系统评价和荟萃分析。
Nutrients. 2022 Mar 18;14(6):1284. doi: 10.3390/nu14061284.
2
Beta-carotene exerted anti-proliferative and apoptotic effect on malignant mesothelioma cells.β-胡萝卜素对恶性间皮瘤细胞具有抗增殖和凋亡作用。
Naunyn Schmiedebergs Arch Pharmacol. 2022 Apr;395(4):407-415. doi: 10.1007/s00210-022-02214-6. Epub 2022 Feb 2.
3
Beta-carotene and its protective effect on gastric cancer.
微藻蛋白质生产的进展与挑战:传统蛋白质来源的可持续替代方案
Microb Cell Fact. 2025 Mar 10;24(1):61. doi: 10.1186/s12934-025-02685-1.
4
Soxhlet extraction of fruit peel for β-carotene recovery.采用索氏提取法从果皮中提取β-胡萝卜素。
RSC Adv. 2025 Feb 28;15(9):6764-6773. doi: 10.1039/d4ra08999e. eCollection 2025 Feb 26.
5
Anticancer Properties of Macroalgae: A Comprehensive Review.大型海藻的抗癌特性:全面综述
Mar Drugs. 2025 Feb 7;23(2):70. doi: 10.3390/md23020070.
6
Algal pigments: Therapeutic potential and food applications.藻类色素:治疗潜力与食品应用
Food Sci Nutr. 2024 Jul 29;12(10):6956-6969. doi: 10.1002/fsn3.4370. eCollection 2024 Oct.
7
Identifying molecular targets for modulating carotenoid accumulation in rice grains.鉴定调控水稻籽粒类胡萝卜素积累的分子靶点。
Biochem Biophys Rep. 2024 Sep 6;40:101815. doi: 10.1016/j.bbrep.2024.101815. eCollection 2024 Dec.
8
Bioguided Optimization of the Nutrition-Health, Antioxidant, and Immunomodulatory Properties of (Cassava) Flour Enriched with Cassava Leaves.富含木薯叶的木薯粉的营养-健康、抗氧化和免疫调节特性的生物导向优化。
Nutrients. 2024 Sep 6;16(17):3023. doi: 10.3390/nu16173023.
9
Impact of rearing systems in the Eastern Amazon on cholesterol, β-carotene and vitamin E homologues in steer.亚马逊东部养殖系统对阉牛胆固醇、β-胡萝卜素和维生素E同系物的影响。
Front Vet Sci. 2024 May 16;11:1331913. doi: 10.3389/fvets.2024.1331913. eCollection 2024.
10
Can Nutraceuticals Support the Treatment of MASLD/MASH, and thus Affect the Process of Liver Fibrosis?营养保健品能否支持 MASLD/MASH 的治疗,从而影响肝纤维化的进程?
Int J Mol Sci. 2024 May 11;25(10):5238. doi: 10.3390/ijms25105238.
β-胡萝卜素及其对胃癌的保护作用。
World J Clin Cases. 2021 Aug 16;9(23):6591-6607. doi: 10.12998/wjcc.v9.i23.6591.
4
Fate of β-Carotene within Loaded Delivery Systems in Food: State of Knowledge.食品中负载递送系统内β-胡萝卜素的命运:知识现状
Antioxidants (Basel). 2021 Mar 10;10(3):426. doi: 10.3390/antiox10030426.
5
The coronavirus disease (COVID-19) - A supportive approach with selected micronutrients.新型冠状病毒病(COVID-19)——选择微量营养素的支持性方法。
Int J Vitam Nutr Res. 2022 Jan;92(1):13-34. doi: 10.1024/0300-9831/a000693. Epub 2021 Jan 25.
6
β-Carotene: Preventive Role for Type 2 Diabetes Mellitus and Obesity: A Review.β-胡萝卜素:预防 2 型糖尿病和肥胖的作用:综述。
Molecules. 2020 Dec 9;25(24):5803. doi: 10.3390/molecules25245803.
7
Nutrition, immunity and COVID-19.营养、免疫与新冠病毒病
BMJ Nutr Prev Health. 2020 May 20;3(1):74-92. doi: 10.1136/bmjnph-2020-000085. eCollection 2020.
8
Enhancing β-Carotene Production in by Perturbing Central Carbon Metabolism and Improving the NADPH Supply.通过扰动中心碳代谢和改善NADPH供应提高[具体对象]中β-胡萝卜素的产量。 (原文中“in”后面缺少具体内容)
Front Bioeng Biotechnol. 2020 Jun 9;8:585. doi: 10.3389/fbioe.2020.00585. eCollection 2020.
9
Nutritional recommendations for CoVID-19 quarantine.新冠病毒隔离期的营养建议。
Eur J Clin Nutr. 2020 Jun;74(6):850-851. doi: 10.1038/s41430-020-0635-2. Epub 2020 Apr 14.
10
The association of dietary patterns and carotid intima-media thickness: A synthesis of current evidence.膳食模式与颈动脉内膜中层厚度的相关性:现有证据的综合分析。
Nutr Metab Cardiovasc Dis. 2019 Dec;29(12):1273-1287. doi: 10.1016/j.numecd.2019.08.014. Epub 2019 Sep 3.