Kumar Virender, Encinosa William
Westat, Rockville, MD.
Agency for Healthcare Research and Quality, Rockville, MD.
Clin Diabetes. 2022 Spring;40(2):185-195. doi: 10.2337/cd20-0122. Epub 2022 Apr 15.
Recent studies of diabetes suggest an obesity paradox: mortality risk increases with weight in people without diabetes but decreases with weight in people with diabetes. A recent study also reports the paradox more generally with health care utilization. Whether this paradox in health care utilization and spending is causal or instead the result of empirical biases and confounding factors has yet to be examined in detail. This study set out to examine changes in the relationship between BMI and health care expenditures in populations with versus without diabetes, controlling for confounding risk factors. It found that the obesity paradox does not exist and is the result of statistical biases such as confounding and reverse causation. Obesity is not cost-saving for people with diabetes. Thus, insurers and physicians should renew efforts to prevent obesity in people with diabetes.
在非糖尿病患者中,死亡风险随体重增加而上升,而在糖尿病患者中,死亡风险随体重增加而下降。最近一项研究还更广泛地报道了医疗保健利用方面的这一悖论。医疗保健利用和支出方面的这一悖论是因果关系,还是实证偏差和混杂因素的结果,尚有待详细研究。本研究旨在考察有无糖尿病的人群中体重指数(BMI)与医疗保健支出之间关系的变化,并控制混杂风险因素。研究发现肥胖悖论并不存在,它是由诸如混杂和反向因果关系等统计偏差导致的。肥胖对于糖尿病患者而言并非节省成本。因此,保险公司和医生应重新努力预防糖尿病患者肥胖。