Vickers A P, Derbyshire D R, Burt D R, Bagshaw P F, Pearson H, Smith G
Br J Anaesth. 1987 Apr;59(4):503-9. doi: 10.1093/bja/59.4.503.
Two devices for providing patient-controlled, on-demand analgesia were compared for 24 h after abdominal surgery. The Leicester Micropalliator delivered a mandatory background infusion of 1 mg h-1 in addition to on demand bolus doses of morphine 2 mg i.v. while the Cardiff Palliator provided only bolus doses of morphine 2 mg i.v. The Leicester Micropalliator provided analgesia superior or equivalent to that of the Cardiff Palliator in patients who had undergone hysterectomy or cholecystectomy, respectively, and there was no increase in side effects. The total doses of morphine administered over 24 h did not differ significantly between the two devices.
对两种用于提供患者自控按需镇痛的装置在腹部手术后24小时进行了比较。莱斯特微型镇痛泵除了按需静脉推注2毫克吗啡外，还强制进行每小时1毫克的背景输注，而加的夫镇痛泵仅提供静脉推注2毫克吗啡。在分别接受子宫切除术或胆囊切除术的患者中，莱斯特微型镇痛泵提供的镇痛效果优于或等同于加的夫镇痛泵，且副作用没有增加。两种装置在24小时内给予的吗啡总剂量没有显著差异。
