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利比亚母婴脐带血中铅浓度的相关性。

Correlation between maternal and fetal umbilical cord blood lead concentrations in Libya.

机构信息

Biotechnology Research Center, Twesha, Tripoli, Libya.

President of the University of Tripoli, Tripoli, Libya.

出版信息

East Mediterr Health J. 2022 May 29;28(5):345-351. doi: 10.26719/emhj.22.020.

DOI:10.26719/emhj.22.020
PMID:35670439
Abstract

BACKGROUND

People are exposed to lead from car exhaust fumes (leaded petrol), lead-based paints, plumbing systems, cigarette smoking, contaminated soil and dust, foods grown in polluted areas, and water sources. Among the vulnerable subpopulations are pregnant women, fetuses and infants.

AIMS

To estimate and correlate maternal and neonatal blood lead levels and compare these between neonates and their mothers in Tripoli and Ghadames.

METHODS

In this cross-sectional study, blood was collected from 120 and 116 mothers and their neonates from Tripoli and Ghadames, respectively. Lead levels were determined using atomic absorption spectrophotometry. A simple questionnaire was filled by the participants using face-to face interview. Data were analysed using SPSS version 20.0 and Excel.

RESULTS

Mean blood and umbilical cord lead levels were 6.83 (standard deviation 4.96) and 6.05 (4.89) µg/dl in mothers and neonates from Tripoli, respectively, and 5.91 (4.02) and 4.54 (4.09) µg/dl from Ghadames. There was no significant difference in blood lead level between mothers from Tripoli and Ghadames. However, there was a significant correlation between maternal blood and umbilical cord blood in Tripoli and Ghadames. Linear regression revealed that neonatal umbilical cord blood lead levels reflected the levels in maternal blood. Blood lead in this study was higher than that reported in industrialized western countries.

CONCLUSION

We detected moderate blood lead levels among pregnant women in Tripoli and Ghadames. It is important to detect the source of lead in the Libyan population to treat this problem effectively.

摘要

背景

人们会通过汽车尾气(含铅汽油)、含铅涂料、管道系统、吸烟、受污染的土壤和灰尘、在污染地区种植的食物以及水源接触到铅。在弱势群体中,孕妇、胎儿和婴儿尤其容易受到影响。

目的

估计和关联母体和新生儿血液中的铅含量,并比较的黎波里和盖达迈的新生儿与其母亲之间的血液铅含量。

方法

在这项横断面研究中,分别从的黎波里和盖达迈的 120 位母亲及其新生儿采集了血液样本。使用原子吸收分光光度法测定了铅含量。参与者使用面对面访谈填写了一份简单的问卷。使用 SPSS 版本 20.0 和 Excel 对数据进行了分析。

结果

来自的黎波里的母亲和新生儿的平均血液和脐血铅含量分别为 6.83(标准差 4.96)和 6.05(4.89)µg/dl,而来自盖达迈的母亲和新生儿的平均血液和脐血铅含量分别为 5.91(标准差 4.02)和 4.54(标准差 4.09)µg/dl。来自的黎波里的母亲的血液铅含量与来自盖达迈的母亲之间没有显著差异。然而,在的黎波里和盖达迈,母亲血液和脐血之间存在显著相关性。线性回归表明,新生儿脐血中的铅含量反映了母亲血液中的铅含量。本研究中的血液铅含量高于工业化西方国家的报告水平。

结论

我们在的黎波里和盖达迈的孕妇中检测到了中等水平的血液铅含量。重要的是,要在利比亚人群中检测铅的来源,以便有效地治疗这个问题。

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