Dermatology Department, Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte, E.P.E., Lisbon, Portugal.
Dermatol Online J. 2022 Mar 15;28(2). doi: 10.5070/D328257395.
Myopericytoma is an uncommon benign neoplasm that arises from the perivascular myoid cells. It typically presents as a painless well-circumscribed cutaneous or soft-tissue nodule, most commonly on the extremities of adults. Histologically, it is characterized by spindle-shaped myoid-appearing cells with a concentric arrangement in vessel walls, that are immunoreactive to alpha-smooth muscle actin and often for h-caldesmon, but negative for other smooth muscle markers. Herein, we present an unusual case of a painful subungual myopericytoma presenting as a dark subungual discoloration.
肌纤维母细胞瘤是一种罕见的良性肿瘤，起源于血管周围的肌样细胞。它通常表现为无痛的界限清楚的皮肤或软组织结节，最常见于成人的四肢。组织学上，它的特征是梭形的肌样外观细胞，在血管壁呈同心排列，对α-平滑肌肌动蛋白和 h-钙调蛋白呈免疫反应性，但对其他平滑肌标志物呈阴性。在此，我们报告了一个不寻常的病例，即疼痛性甲下肌纤维母细胞瘤表现为暗甲下变色。
