人类内源性逆转录病毒如何在健康和疾病中与微生物组相互作用。

How human endogenous retroviruses interact with the microbiota in health and disease.

机构信息

Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, NY 10021, USA.

出版信息

Trends Microbiol. 2022 Sep;30(9):812-815. doi: 10.1016/j.tim.2022.05.011. Epub 2022 Jun 5.

DOI:10.1016/j.tim.2022.05.011

Abstract

The microbiota is a collective of microorganisms whose composition is intimately linked with human health and disease. Emerging evidence demonstrates that endogenous retroviruses facilitate crosstalk between the host and microbiota to fundamentally shape immunity.

摘要

微生物组是微生物的集合体，其组成与人类健康和疾病密切相关。新出现的证据表明，内源性逆转录病毒促进了宿主与微生物组之间的交流，从而从根本上塑造了免疫。