Reveley M A, De Belleroche J, Recordati A, Hirsch S R
Biol Psychiatry. 1987 Apr;22(4):413-20. doi: 10.1016/0006-3223(87)90163-6.
We found significantly higher levels of cerebrospinal fluid alanine, glycine, leucine, and phenylalanine in schizophrenic patients compared to healthy controls. Ventricular enlargement was present in 4 of 11 schizophrenics, and elevated CSF alanine was highly correlated with ventricular enlargement. The implications of these findings are discussed.
我们发现,与健康对照组相比,精神分裂症患者脑脊液中的丙氨酸、甘氨酸、亮氨酸和苯丙氨酸水平显著更高。11名精神分裂症患者中有4人存在脑室扩大,脑脊液丙氨酸水平升高与脑室扩大高度相关。本文讨论了这些发现的意义。