IRCCS Orthopedic Institute Galeazzi, Milan, Italy.
Department of Biomedical Sciences for Health, University of Milan, 20133, Milan, Italy.
Int Orthop. 2022 Sep;46(9):2029-2039. doi: 10.1007/s00264-022-05465-3. Epub 2022 Jun 8.
The aim of this study is to compare the functional outcomes and osteoarthritis (OA) progression after anterior cruciate ligament (ACL) reconstruction with either hamstring autografts or allografts in people over 50.
The clinical records of two consecutive cohorts of 61 cases in total over 50 years of age, undergoing ACL reconstruction, were included. The first cohort consisted of 29 allografts; the second cohort consisted of 32 autologous hamstring tendon grafts. The cases were evaluated pre- (T) and post-operatively at six months (T), 12 months (T) and 24 months (T). Clinical examination included the Lachman test, pivot shift test and objective (Objective IKDC [The International Knee Documentation Committee] score) and subjective clinical scores (Subjective IKDC score, Lysholm score and Tegner activity score). The degree of OA was evaluated using the Kellgren-Lawrence system at the time of the final follow-up, compared to the pre-operative condition.
No pre-operative difference was found between the two groups (p > 0.05). No statistical difference was noted between the two groups at each follow-up (p > 0.05). At the final follow-up, both the groups significantly improved statistically in all the clinical and functional scores (p < 0.05). In both groups, one graft re-rupture was noted. No progression of OA was noted in both groups at final follow-up (p > 0.05).
The graft choice does not influence the outcomes two years after ACL reconstruction in people over 50; thus, both treatments help in regaining knee stability with no signs of OA progression.
Researchregistry7539- www.researchregistry.com .
本研究旨在比较 50 岁以上人群前交叉韧带(ACL)重建后使用自体或同种异体移植物的功能结果和骨关节炎(OA)进展。
共纳入两批连续队列共 61 例 50 岁以上患者的临床资料,均行 ACL 重建。第一队列包括 29 例同种异体移植物;第二队列包括 32 例自体腘绳肌腱移植物。病例在术前(T)和术后 6 个月(T)、12 个月(T)和 24 个月(T)进行评估。临床检查包括lachman 试验、前抽屉试验和客观(国际膝关节文献委员会客观评分[IKDC])和主观临床评分(IKDC 主观评分、Lysholm 评分和 Tegner 活动评分)。在最终随访时,根据 Kellgren-Lawrence 系统评估 OA 程度,并与术前情况进行比较。
两组患者在术前无差异(p>0.05)。两组患者在每次随访时均无统计学差异(p>0.05)。在最终随访时,两组患者在所有临床和功能评分上均有显著改善(p<0.05)。两组均有 1 例移植物再断裂。两组患者在最终随访时均未见 OA 进展(p>0.05)。
在 50 岁以上人群中,ACL 重建后 2 年,移植物的选择并不影响结果;因此,两种治疗方法都有助于恢复膝关节稳定性,且无 OA 进展的迹象。
Researchregistry7539- www.researchregistry.com 。