Piedbois P, Bataïni P, Jaulerry C, Brunin F, Pontvert D, Nguyen L
Bull Cancer. 1986;73(6):665-74.
From 1955 through 1982, a series of 93 cases of parotid gland carcinoma were treated at the Institut Curie: 55 primarily and 28 for recurrent tumors. Treatment modalities included surgery alone (n : 14), surgery followed by radiotherapy (n : 43), and radiotherapy alone (n : 36). The most advanced cases were mostly in the latter group. With a mean follow-up of 13 years, the actuarial loco-regional control is 67% (62/93) and the median survival 10 years. Ultimate loco-regional control was achieved in 86% of cases managed by surgery alone, 88% of cases managed by surgery and radiotherapy and 33% of cases managed by radiotherapy. In the latter group, control rate was 42% (8/19) in those primarily treated by radiotherapy. Prognosis was related to histology. Twenty patients (22%) presented distant metastasis. The potential advantages of neutron irradiation for parotid neoplasms is discussed.
1955年至1982年期间,居里研究所共治疗了93例腮腺癌患者:55例为原发性肿瘤,28例为复发性肿瘤。治疗方式包括单纯手术(n = 14)、手术加放疗(n = 43)和单纯放疗(n = 36)。病情最严重的病例大多在最后一组。平均随访13年,精算局部区域控制率为67%(62/93),中位生存期为10年。单纯手术治疗的病例中,86%实现了最终局部区域控制;手术加放疗治疗的病例中,88%实现了最终局部区域控制;单纯放疗治疗的病例中,33%实现了最终局部区域控制。在最后一组中,初治采用放疗的患者控制率为42%(8/19)。预后与组织学有关。20例患者(22%)出现远处转移。本文讨论了中子照射对腮腺肿瘤的潜在优势。