Universidade Federal de Goiás, Rio Verde, GO - Brasil.
Universidade Federal de Jataí - Medicina, Jataí, GO - Brasil.
Arq Bras Cardiol. 2022 Aug;119(2):257-264. doi: 10.36660/abc.20210432.
Arterial stiffness is a strong predictor of cardiovascular disease (CVD). Body fat measures such as waist circumference (WC) have been associated with CVD in adulthood.
The objective of this study was to evaluate the association of arterial stiffness, measured by applanation tonometry-Sphygmocor, with WC.
Observational study with 240 participants who make routine consultations at the outpatient clinic of a university hospital. Participants were interviewed and had central blood pressure measurements (CBPM), anthropometric parameters, abdominal fat and visceral fat measured. Paired and unpaired t and chi-square tests were used. A significance level of 5% was adopted.
Of the 240 participants, 51.82% were male with a mean age of 59.71(±14.81) years and a mean WC of 99.87 (11.54) cm. Mean CBPM values were: Central arterial pressure (CAP) = 130.23 (91-223) mmHg, pulse wave velocity (PWV) = 9.8 (5.28-19.6)m/s and Augmentation Index [Amplification Index (AI)] = 29.45 (-14-60). PWV and CAP were highly correlated with WC with p<0.001 and p=0.02, respectively; however, the same positive correlation was not found between WC and AI (p=0.06).
The present study showed a positive association between WC and arterial stiffness, through the femoral carotid pulse wave velocity (cf-PWV) and AI, being stronger with cf-PWV, suggesting the evaluation of the effect of WC in vascular health as a method of aid in the early treatment of CVD and in the prevention of clinical outcomes.
动脉僵硬度是心血管疾病（CVD）的强有力预测指标。腰围（WC）等体脂测量值与成年人心血管疾病有关。
本研究旨在评估平板张力测量法-Sphygmocor 测量的动脉僵硬度与 WC 的相关性。
这是一项观察性研究，共纳入 240 名在大学医院门诊进行常规就诊的参与者。对参与者进行访谈，并进行中心血压测量（CBPM）、人体测量参数、腹部脂肪和内脏脂肪测量。使用配对和非配对 t 检验和卡方检验。采用 5%的显著性水平。
240 名参与者中，51.82%为男性，平均年龄 59.71（±14.81）岁，平均 WC 为 99.87（11.54）cm。平均 CBPM 值为：中心动脉压（CAP）=130.23（91-223）mmHg，脉搏波速度（PWV）=9.8（5.28-19.6）m/s，增强指数[放大指数（AI）]=29.45（-14-60）。PWV 和 CAP 与 WC 高度相关，p<0.001 和 p=0.02；然而，WC 与 AI 之间没有发现相同的正相关关系（p=0.06）。
本研究表明，WC 与动脉僵硬度之间存在正相关，通过股颈动脉脉搏波速度（cf-PWV）和 AI 表现出来，与 cf-PWV 的相关性更强，这表明评估 WC 对血管健康的影响作为 CVD 早期治疗和预防临床结局的辅助方法的效果。
