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阿糖腺苷和碘苷治疗单纯疱疹和带状疱疹的双盲试验。

Double blind trial in the treatment of herpes simplex and herpes zoster with adenine arabinoside and idoxuridine.

作者信息

Theodoridis A, Sivenas C, Vagena A, Capetanakis J

出版信息

Arch Dermatol Res. 1978 Jul 28;262(2):173-6. doi: 10.1007/BF00455387.

Abstract

In a double blind trial adenine arabinoside (Vidarabine) and Idoxuridine (IDU) were tested in herpes simplex and herpes zoster infections. Adenine arabinoside covered 19 patients with HSV and 6 with HZ while IDU 19 with HSV and 6 with HZ. From the statistical analysis it was found that Vidarabine acts shorter than IDU in HSV P less than 0.01, while in HZ no significant difference P less than 0.5 was found, possibly due to the small number of patients tested.

摘要

在一项双盲试验中,对阿糖腺苷(阿糖腺嘌呤)和碘苷进行了单纯疱疹和带状疱疹感染方面的测试。阿糖腺苷治疗了19例单纯疱疹病毒(HSV)感染患者和6例带状疱疹(HZ)感染患者,而碘苷治疗了19例HSV感染患者和6例HZ感染患者。通过统计分析发现,在HSV感染中,阿糖腺苷的作用时间比碘苷短(P<0.01),而在HZ感染中,未发现显著差异(P<0.5),这可能是由于受试患者数量较少。

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