通过白血病干细胞切入肿瘤学和代谢学的融合。
Biting into a union of oncology and metabolism through leukemic stem cells.
机构信息
Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada.
Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada.
出版信息
Cell Metab. 2022 Jun 7;34(6):801-802. doi: 10.1016/j.cmet.2022.05.006.
PMID:35675797
Abstract
In this issue of Cell Metabolism, Liu et al. demonstrate that Prmt7 can regulate the onset and progression of leukemogenesis by inhibiting self-renewal capacity of leukemic stem cells (LSCs) as modeled in a murine version of chronic myeloid leukemia (CML).
摘要
在本期《细胞代谢》中，Liu 等人证明，PRMT7 可通过抑制慢性髓系白血病（CML）小鼠模型中的白血病干细胞（LSCs）的自我更新能力来调节白血病的发生和进展。
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