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衰老会降低清醒猫尾状核神经元的体感反应能力。

Aging reduces somatosensory responsiveness of caudate neurons in the awake cat.

作者信息

Levine M S, Schneider J S, Lloyd R L, Hull C D, Buchwald N A

出版信息

Brain Res. 1987 Mar 10;405(2):389-94. doi: 10.1016/0006-8993(87)90312-x.

DOI:10.1016/0006-8993(87)90312-x
PMID:3567616
Abstract

Neuronal activity was recorded in 7 awake cats (3 animals 11-15 years and 4 animals 1-3 years of age) to determine if the ability of caudate neurons to process facial somatosensory information was impaired in aged animals. Proportionately fewer neurons responded to somatosensory stimuli and facial receptive fields were larger in the aged cats. In addition, proportionately fewer caudate neurons responded to cortical activation, there were fewer excitatory responses and spontaneous firing decreasing in aged cats. These results provide additional evidence that excitability of caudate neurons is reduced in aged cats.

摘要

记录了7只清醒猫(3只11 - 15岁的动物和4只1 - 3岁的动物)的神经元活动,以确定老年动物尾状核神经元处理面部体感信息的能力是否受损。在老年猫中,对体感刺激作出反应的神经元比例相对较少,且面部感受野更大。此外,尾状核神经元对皮层激活作出反应的比例也相对较少,兴奋性反应减少,老年猫的自发放电也减少。这些结果提供了额外的证据,表明老年猫尾状核神经元的兴奋性降低。

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