Lawani Osayi, Winter Mark
University of Houston College of Medicine/HCA Houston Healthcare, USA.
Southeast Texas Poison Center, University of Texas Medical Branch, USA.
Case Rep Cardiol. 2022 May 30;2022:3679968. doi: 10.1155/2022/3679968. eCollection 2022.
The candlenut tree is a tropical plant that has a vast number of uses which include fertilizer, dye, ink for tattooing, and fuel. The inner seed of the nut is the most utilized portion of the plant and is often sold as a food additive, natural laxative, or a weight loss supplement. Unfortunately, the seed itself is very toxic when consumed whole and in its raw state. Typical symptoms of toxicity include abdominal pain, vomiting, and diarrhea. Rarely, it can cause cardiac dysrhythmias, most commonly bradycardia and atrioventricular heart block. We present a case of a young adult female with no significant past medical history who developed typical symptoms of toxicity, as well as atrioventricular heart block following ingestion of a candlenut. Most documented cases describe complete resolution of gastrointestinal and cardiac symptoms about one week following ingestion; however, treatment while inpatient can consist of inotropes or vasopressor support, intravenous fluid hydration, electrolyte replacement, and antiemetics. Although the mechanism of action remains unclear, this report provides physicians with an understanding of the risks of ingestion and the knowledge of typical management of the toxic effects of the candlenut.
桐油树是一种热带植物,有多种用途,包括用作肥料、染料、纹身墨水和燃料。坚果的内籽是该植物利用最多的部分,常作为食品添加剂、天然泻药或减肥补充剂出售。不幸的是,种子整颗生食时毒性很强。中毒的典型症状包括腹痛、呕吐和腹泻。很少情况下,它会导致心律失常,最常见的是心动过缓和房室传导阻滞。我们报告一例无重大既往病史的年轻成年女性,在食用桐油果后出现典型中毒症状及房室传导阻滞。大多数记录在案的病例表明,摄入后约一周胃肠道和心脏症状完全缓解;然而,住院治疗可包括使用正性肌力药物或血管活性药物支持、静脉补液、补充电解质和使用止吐药。虽然作用机制尚不清楚,但本报告让医生了解了摄入桐油果的风险以及对其毒性作用的典型处理方法。