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巴西脂肪性水肿的患病率及风险因素。

Lipedema prevalence and risk factors in Brazil.

作者信息

Amato Alexandre Campos Moraes, Amato Fernando Campos Moraes, Amato Juliana Lelis Spirandeli, Benitti Daniel Augusto

机构信息

Amato, Instituto de Medicina Avançada, São Paulo, SP, Brasil.

Valens Medical Center, Campinas, SP, Brasil.

出版信息

J Vasc Bras. 2022 May 23;21:e20210198. doi: 10.1590/1677-5449.202101981. eCollection 2022.

DOI:10.1590/1677-5449.202101981
PMID:35677743
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9136687/
Abstract

BACKGROUND

Lipedema is characterized as an abnormal deposition of fat in the buttocks and legs bilaterally that may be accompanied by swelling, pain, and tenderness. It is still often confused with more frequent conditions such as obesity and lymphedema. The estimated prevalence in Europe varies between 0.06% and 39%.

OBJECTIVES

To evaluate the prevalence of lipedema and identify health factors related to it in the Brazilian population.

METHODS

Administration of a previously validated online screening questionnaire to a representative sample of the general population. The questionnaire was distributed and administered to anonymous volunteers representing the general Brazilian population using software designed for population analyses.

RESULTS

253 women answered the questionnaire, 12.3 ± 4% (Confidence Interval [CI] 95%) of whom presented symptoms compatible with a high probability of being diagnosed with lipedema. Furthermore, anxiety, depression, hypertension, and anemia were also correlated with a high probability of the diagnosis.

CONCLUSIONS

The estimated prevalence of lipedema in the population of Brazilian women is 12.3%.

摘要

背景

脂肪性水肿的特征是双侧臀部和腿部出现异常脂肪沉积,可能伴有肿胀、疼痛和压痛。它仍常常与肥胖和淋巴水肿等更常见的病症相混淆。欧洲的估计患病率在0.06%至39%之间。

目的

评估巴西人群中脂肪性水肿的患病率,并确定与之相关的健康因素。

方法

对一般人群的代表性样本进行预先验证的在线筛查问卷。使用为人群分析设计的软件,将问卷分发给代表巴西一般人群的匿名志愿者并进行管理。

结果

253名女性回答了问卷,其中12.3±4%(95%置信区间[CI])的人出现了与极有可能被诊断为脂肪性水肿相符的症状。此外,焦虑、抑郁、高血压和贫血也与高诊断概率相关。

结论

巴西女性人群中脂肪性水肿的估计患病率为12.3%。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134c/9136687/a76c2564507e/jvb-21-e20210198-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134c/9136687/5e41cddb96e8/jvb-21-e20210198-g01-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134c/9136687/e7fbde1d2874/jvb-21-e20210198-g02-en.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134c/9136687/317533a707d2/jvb-21-e20210198-g04-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134c/9136687/5e41cddb96e8/jvb-21-e20210198-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134c/9136687/25b828e7a57c/jvb-21-e20210198-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134c/9136687/a309e520b328/jvb-21-e20210198-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134c/9136687/a76c2564507e/jvb-21-e20210198-g04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134c/9136687/5e41cddb96e8/jvb-21-e20210198-g01-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134c/9136687/e7fbde1d2874/jvb-21-e20210198-g02-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134c/9136687/b84b442b308a/jvb-21-e20210198-g03-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134c/9136687/317533a707d2/jvb-21-e20210198-g04-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134c/9136687/5e41cddb96e8/jvb-21-e20210198-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134c/9136687/25b828e7a57c/jvb-21-e20210198-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134c/9136687/a309e520b328/jvb-21-e20210198-g03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/134c/9136687/a76c2564507e/jvb-21-e20210198-g04.jpg

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本文引用的文献

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J Vasc Bras. 2020 Dec 11;19:e20200114. doi: 10.1590/1677-5449.200114.
2
Translation, cultural adaptation, and validation of a lipedema symptoms questionnaire.脂肪性水肿症状问卷的翻译、文化调适与验证
J Vasc Bras. 2020 Aug 31;19:e20200049. doi: 10.1590/1677-5449.200049.
3
Standard of care for lipedema in the United States.美国脂性水肿的护理标准。
男性脂肪性水肿:来自巴西一家转诊中心的5例患者回顾性病例系列
Cureus. 2025 Jul 5;17(7):e87332. doi: 10.7759/cureus.87332. eCollection 2025 Jul.
4
Lipedema: Clinical Features, Diagnosis, and Management.脂肪性水肿:临床特征、诊断与管理
Arch Plast Surg. 2025 May 15;52(3):185-196. doi: 10.1055/a-2530-5875. eCollection 2025 May.
5
Brazilian Consensus Statement on Lipedema using the Delphi methodology.采用德尔菲法的巴西脂肪性水肿共识声明。
J Vasc Bras. 2025 Feb 10;24:e20230183. doi: 10.1590/1677-5449.202301832. eCollection 2025.
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Lipedema: exploring pathophysiology and treatment strategies - state of the art.脂肪性水肿:探索病理生理学与治疗策略——最新进展
J Vasc Bras. 2025 Jan 20;23:e20240025. doi: 10.1590/1677-5449.202400252. eCollection 2024.
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Lipedema: clinical characteristics, complications, and the importance of evidence-based practice.脂肪性水肿:临床特征、并发症及循证医学实践的重要性
Rev Assoc Med Bras (1992). 2024 Sep 13;70(9):e20240801. doi: 10.1590/1806-9282.20240801. eCollection 2024.
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Efficacy of Liposuction in the Treatment of Lipedema: A Meta-Analysis.抽脂术治疗脂肪性水肿的疗效:一项荟萃分析。
Cureus. 2024 Feb 29;16(2):e55260. doi: 10.7759/cureus.55260. eCollection 2024 Feb.
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Cureus. 2023 Jul 9;15(7):e41594. doi: 10.7759/cureus.41594. eCollection 2023 Jul.
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Phlebology. 2021 Dec;36(10):779-796. doi: 10.1177/02683555211015887. Epub 2021 May 28.
4
Ultrasound criteria for lipedema diagnosis.脂肪水肿的超声诊断标准。
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5
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