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脂肪性水肿问卷及筛查模型的开发。

Development of a questionnaire and screening model for lipedema.

作者信息

Amato Alexandre Campos Moraes, Amato Fernando Campos Moraes, Benitti Daniel Augusto, Amato Lorena Guimarães Lima

机构信息

Universidade Santo Amaro - UNISA, São Paulo, SP, Brasil.

Amato - Instituto de Medicina Avançada, São Paulo, SP, Brasil.

出版信息

J Vasc Bras. 2020 Dec 11;19:e20200114. doi: 10.1590/1677-5449.200114.

DOI:10.1590/1677-5449.200114
PMID:34211528
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8218007/
Abstract

BACKGROUND

Lipedema is greatly underdiagnosed and there is a lack of low-cost tools to facilitate diagnostic. We created a lipedema screening questionnaire based on a questionnaire for assessing symptoms.

OBJECTIVES

The study objectives were to identify relevant clinical questions, develop a screening questionnaire, and construct a model for predicting lipedema.

METHOD

A simplified questionnaire was constructed and administered to a sample of patients with and without lipedema and then the probability of correct diagnosis was analyzed.

RESULTS

All 109 patients who answered the questionnaire were female and all of them understood the questions. A predictive model using individual question scores achieved an excellent probability of correct diagnosis, at 91.2%, and a predictive model based on total score also achieved a good probability of correct diagnosis, at 86.15%.

CONCLUSIONS

The lipedema screening questionnaire is a practical instrument that is quick and easy to administer and can be used with our population for identification of possible lipedema patients, raising the level of suspicion when taking a patient's history and conducting a physical examination.

摘要

背景

脂肪性水肿的诊断严重不足,且缺乏低成本的诊断工具。我们基于一份症状评估问卷创建了一份脂肪性水肿筛查问卷。

目的

本研究的目的是确定相关临床问题,开发一份筛查问卷,并构建一个预测脂肪性水肿的模型。

方法

构建一份简化问卷,并对有和没有脂肪性水肿的患者样本进行调查,然后分析正确诊断的概率。

结果

回答问卷的109名患者均为女性,且都理解问题。使用单个问题得分的预测模型正确诊断概率极佳,为91.2%,基于总分的预测模型正确诊断概率也良好,为86.15%。

结论

脂肪性水肿筛查问卷是一种实用工具,快速且易于实施,可用于我们的人群以识别可能的脂肪性水肿患者,在采集患者病史和进行体格检查时提高怀疑程度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58dd/8218007/2832f5164210/jvb-19-e20200114-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58dd/8218007/8a9d5a8f010f/jvb-19-e20200114-g01-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58dd/8218007/0254cb23b063/jvb-19-e20200114-g02-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58dd/8218007/53388ade93f7/jvb-19-e20200114-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58dd/8218007/2832f5164210/jvb-19-e20200114-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58dd/8218007/8a9d5a8f010f/jvb-19-e20200114-g01-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58dd/8218007/0254cb23b063/jvb-19-e20200114-g02-en.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58dd/8218007/53388ade93f7/jvb-19-e20200114-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58dd/8218007/2832f5164210/jvb-19-e20200114-g02.jpg

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Platelet factor 4 is a biomarker for lymphatic-promoted disorders.血小板因子 4 是一种淋巴促进性疾病的生物标志物。
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Lipedema: an overview of its clinical manifestations, diagnosis and treatment of the disproportional fatty deposition syndrome - systematic review.脂肪性水肿:不成比例脂肪沉积综合征的临床表现、诊断及治疗概述——系统评价
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Thick legs - not always lipedema.腿部粗壮 - 不一定是脂肪水肿。
脂肪性水肿:探索病理生理学与治疗策略——最新进展
J Vasc Bras. 2025 Jan 20;23:e20240025. doi: 10.1590/1677-5449.202400252. eCollection 2024.
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The Association Between Lipedema and Attention-Deficit/Hyperactivity Disorder.脂肪性水肿与注意力缺陷多动障碍之间的关联
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Lipedema prevalence and risk factors in Brazil.巴西脂肪性水肿的患病率及风险因素。
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