自主神经功能测试在直立不耐受的长新冠综合征患者中的应用。
Autonomic function testing in long-COVID syndrome patients with orthostatic intolerance.
机构信息
Department of Neurology, State University of New York, Upstate Medical University, Syracuse, NY 13210, USA; Department of Pathology, State University of New York, Upstate Medical University, Syracuse, NY 13210, USA.
Department of Neurology, State University of New York, Upstate Medical University, Syracuse, NY 13210, USA.
出版信息
Auton Neurosci. 2022 Sep;241:102997. doi: 10.1016/j.autneu.2022.102997. Epub 2022 Jun 2.
The association between dysautonomia and long-COVID syndrome has gained considerable interest. This study retrospectively characterized the findings of autonomic reflex screen (ARS) in long-COVID patients presenting with orthostatic intolerance (OI). Fourteen patients were identified. All patients had normal cardiovagal function and 2 patients had abnormal sudomotor function. The head-up tilt table (HUTT) was significantly abnormal in 3 patients showing postural orthostatic tachycardia syndrome (POTS). CASS ranged from 0 to 2. The most common clinical scenario was symptoms of orthostatic intolerance without demonstrable HUTT orthostatic tachycardia or orthostatic hypotension (OH) (n = 8, 57 %). In our case series, most long-COVID patients presenting to our laboratory with OI had no significant HUTT abnormalities; only 3 patients met the criteria for POTS.
自主神经功能障碍与长新冠综合征之间的关联引起了相当大的关注。本研究回顾性分析了表现为直立不耐受（OI）的长新冠患者自主反射检查（ARS）的结果。共确定了 14 名患者。所有患者的心迷走神经功能正常，2 名患者的自主神经汗腺功能异常。3 名患者的直立倾斜试验（HUTT）明显异常，表现为体位性心动过速综合征（POTS）。CASS 范围为 0 至 2。最常见的临床情况是直立不耐受症状，但 HUTT 直立性心动过速或直立性低血压（OH）无明显异常（n=8，57%）。在我们的病例系列中，大多数因 OI 就诊于我们实验室的长新冠患者的 HUTT 异常不明显；只有 3 名患者符合 POTS 的标准。
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