14 天+7 天的隔离期和双核酸检测试剂策略在中国厦门发现了可能未被发现的 2019 年冠状病毒病感染。
A 14+7 day quarantine period and a dual nucleic acid testing reagent strategy detect potentially indiscoverable Coronavirus disease 2019 infections in Xiamen, China.
机构信息
Center of Clinical Laboratory, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China; Institute of Infectious Disease, School of Medicine, Xiamen University, Xiamen, China.
Center of Clinical Laboratory, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, China; Xiamen Zhongshan Hospital, Fujian Medical University, Xiamen 361004, China.
出版信息
Clin Chim Acta. 2022 Jul 1;532:89-94. doi: 10.1016/j.cca.2022.06.006. Epub 2022 Jun 6.
BACKGROUND
Determining what quarantine period and detection strategy are more effective and sustainable remains a challenge for further prevention and social stability.
METHODS
From October 2020 to December 2021, 290,547 inbound overseas travelers were subject to government quarantine in Xiamen, China. The detection rate of COVID-19 during different quarantine periods using dual or single nucleic acid testing reagents.
RESULTS
The COVID-19 positive rate was 1.79% (519/290,547). The detection rates during the 7-day, 14-day and 14+7-day quarantine periods using the dual reagents were 78.4%, 91.7%, and 100%, respectively. The detection rate of the 7-day, 14-day and 14+7-day quarantine periods were 73.99%, 86.51%, and 94.22%, respectively, using the Liferiver reagent and 72.25%, 84.59%, and 91.91%, respectively, using the Daan reagent. Based on the 14+7 day strategy, dual nucleic acid testing reagent strategy detected all imported cases, but 30 cases (5.78%) were not detected via Liferiver reagent and 42 (8.09%) cases not detected via Daan reagent.
CONCLUSION
A 14+7-day quarantine period and dual nucleic acid testing reagent strategy are effective screening methods for COVID-19 among inbound overseas travelers. The superior detection rate of these strategies reduce the risk of secondary transmission of the SARS-CoV-2 virus.
背景
确定哪种隔离期和检测策略更有效且可持续，仍然是进一步预防和社会稳定的挑战。
方法
2020 年 10 月至 2021 年 12 月，在中国厦门，对 290547 名入境海外旅行者实施政府隔离。使用双或单核酸检测试剂检测不同隔离期的 COVID-19 检出率。
结果
COVID-19 阳性率为 1.79%（519/290547）。使用双试剂进行 7 天、14 天和 14+7 天隔离期的检测率分别为 78.4%、91.7%和 100%。使用 Liferiver 试剂进行 7 天、14 天和 14+7 天隔离期的检测率分别为 73.99%、86.51%和 94.22%，使用 Daan 试剂的检测率分别为 72.25%、84.59%和 91.91%。基于 14+7 天策略，双核酸检测试剂策略检测到了所有输入性病例，但 Liferiver 试剂未检测到 30 例（5.78%），Daan 试剂未检测到 42 例（8.09%）。
结论
14+7 天隔离期和双核酸检测试剂策略是对入境海外旅行者进行 COVID-19 筛查的有效方法。这些策略的高检出率降低了 SARS-CoV-2 病毒二次传播的风险。
Zotero 插件