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隔离设施中返回旅行者的 COVID-19 发病率:一项纵向研究及经验教训。

Incidence of COVID-19 among returning travelers in quarantine facilities: A longitudinal study and lessons learned.

机构信息

Specialty Internal Medicine and Quality Department, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia; Infectious Disease Division, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA; Infectious Disease Division, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Primary Care Division, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia.

出版信息

Travel Med Infect Dis. 2020 Nov-Dec;38:101901. doi: 10.1016/j.tmaid.2020.101901. Epub 2020 Oct 10.

Abstract

INTRODUCTION

The emergence of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) had resulted in an unpresented global pandemic. In the initial events, the Kingdom of Saudi Arabia implemented mandatory quarantine of returning travelers in order to contain COVID-19 cases.

MATERIALS AND METHODS

This is a longitudinal study of the arriving travelers to Quarantine facilities and the prevalence of positive SARS-CoV-2 as detected by RT-PCR.

RESULTS

During the study period, there was a total of 1928 returning travelers with 1273 (66%) males. The age range was 28 days-69 years. Of all the travelers, 23 (1.2%) tested positive for SARS-CoV-2. Of the first swab, 14/1928 (0.7%) tested positive. The positivity rate was 0.63% and 0.92% among males and females, respectively (P = 0.57). The second swab was positive in 9 (0.5%) of the other 1914 who were initially negative with a positivity rate of 0.39% and 0.62% among males and females, respectively (P = 0.49). There was no statistical difference in the positivity rates between first and second swab (P = 0.4). Of all travelers, 40 (n = 26, 1.3%) were admitted from the quarantine facility to the hospital due to COVID-19 related positive results or development of symptoms such as fever, cough, and respiratory symptoms; and 14 (0.7%) were admitted due to non-COVID-19 related illness.

CONCLUSION

This study showed the efforts put for facility quarantine and that such activity yielded a lower incidence of positive cases. There was a need to have a backup healthcare facility to accommodate those developing a medical need for evaluation and admission for non-COVID-19 related illnesses.

摘要

简介

严重急性呼吸综合征冠状病毒 2 (SARS-CoV-2)的出现导致了前所未有的全球大流行。在最初的阶段,沙特阿拉伯王国对返回的旅行者实施了强制性隔离,以控制 COVID-19 病例。

材料与方法

这是一项对隔离设施中抵达旅行者的纵向研究,以及通过 RT-PCR 检测到的 SARS-CoV-2 阳性的流行率。

结果

在研究期间,共有 1928 名返回的旅行者,其中 1273 名(66%)为男性。年龄范围为 28 天至 69 岁。所有旅行者中,有 23 人(1.2%)检测出 SARS-CoV-2 阳性。在 1928 名旅行者中,有 14 人(0.7%)第一次拭子检测呈阳性。男性和女性的阳性率分别为 0.63%和 0.92%(P=0.57)。在最初检测呈阴性的 1914 名其他旅行者中,第二次拭子检测有 9 人(0.5%)呈阳性,男性和女性的阳性率分别为 0.39%和 0.62%(P=0.49)。第一次和第二次拭子检测的阳性率没有统计学差异(P=0.4)。在所有旅行者中,有 40 人(n=26,1.3%)因 COVID-19 阳性结果或出现发热、咳嗽和呼吸道症状等症状而从隔离设施被送往医院;有 14 人(0.7%)因非 COVID-19 相关疾病而住院。

结论

本研究表明,沙特阿拉伯王国为设施隔离所做的努力取得了较低的阳性病例发生率。需要有一个后备医疗设施,以容纳那些因非 COVID-19 相关疾病而需要评估和住院的人。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3376/7547317/0811b7777cb0/gr1_lrg.jpg

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