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因食物接触尘导致的锌和铜吸入性肺损伤

Acute inhalation lung injury secondary to zinc and copper aspiration from food contact dust.

机构信息

Department of Women's and Children's Health, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK

NIHR Clinical Research Facility, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.

出版信息

BMJ Case Rep. 2022 Jun 9;15(6):e250152. doi: 10.1136/bcr-2022-250152.

Abstract

A previously healthy boy of preschool age was brought to the emergency department by ambulance with respiratory distress following the accidental inhalation of food contact dust (cake decorating powder). Prehospital oxygen saturations were 80% in room air. Initial treatment was with oxygen, nebulised salbutamol, oral dexamethasone and intravenous amoxicillin/clavulanic acid. Treatment was escalated to nasal high flow oxygen therapy and high dependency care within 8 hours. Lung fields on his initial chest X-ray were clear but the following day showed perihilar infiltrates extending into the lower zones in keeping with inflammation. He was treated with intravenous methylprednisolone, followed by a weaning dose of oral prednisolone over 14 days.He required oxygen therapy for 9 days and remained in hospital for 11 days. Outpatient follow-up, 24 days after the inhalation took place was reassuring with the child showing no signs of abnormal respiratory symptoms.

摘要

一名学龄前健康男童在意外吸入食物接触粉尘(蛋糕装饰粉)后出现呼吸窘迫,由救护车送往急诊部。入院前室内空气氧饱和度为 80%。初始治疗包括吸氧、沙丁胺醇雾化吸入、口服地塞米松和静脉用阿莫西林/克拉维酸。8 小时内治疗升级为经鼻高流量氧疗和高依赖护理。最初的胸部 X 线显示双肺野清晰,但次日显示肺门周围浸润延伸至下区,符合炎症表现。他接受了静脉甲基强的松龙治疗,随后在 14 天内逐渐减少口服泼尼松剂量。他需要氧疗 9 天,住院 11 天。吸入后 24 天的门诊随访结果令人安心,患儿无任何异常呼吸症状。

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本文引用的文献

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Acute inhalation injury.急性吸入性损伤
Eurasian J Med. 2010 Apr;42(1):28-35. doi: 10.5152/eajm.2010.09.
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Acute respiratory failure in a child after talc inhalation.滑石粉吸入后儿童急性呼吸衰竭
Respiration. 2010;79(4):340. doi: 10.1159/000181013. Epub 2008 Dec 2.

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