Zhou Yaxi, Zhou Shiqi, Duan Hao, Wang Jing, Yan Wenjie
College of Biochemical Engineering, Beijing Union University, No. 18, Caili District 3, Futou, Beijing 100023, China.
Beijing Key Laboratory of Bioactive Substances and Functional Food, College of Biochemical Engineering, Beijing Union University, 197 North Tucheng West Road, Beijing 100023, China.
Foods. 2022 May 28;11(11):1594. doi: 10.3390/foods11111594.
Silkworm pupae are insects that are beneficial to human health, not only for their high nutritional value but, more importantly, for the variety of pharmacological functions they can perform when consumed. Currently, there is a lot of interest in the pharmaceutical applications of silkworm pupae. In recent years, the biological functions of domestic silkworm pupae have gradually been identified and confirmed, especially for their beneficial effects on human health. Studies have found that silkworm pupae have positive effects on liver protection, immune enhancement, antiapoptosis, antitumour, antibacterial, regulation of blood glucose and blood lipids, and lowering of blood pressure. However, the pharmacological mechanisms and systemic safety of silkworm pupae have not been systematically evaluated. In this paper, the nutritional composition of the pupae of the domestic silkworm is first summarised. The pharmacological functions of silkworm pupae and their components are then classified, and their mechanisms of occurrence are described. In addition, we provide a preliminary evaluation of the safety of silkworm pupae, analyse their application prospects, and suggest future directions for further pharmacological function studies. The aim is to generate interest in the promotion of human health through the use of silkworm pupae.
蚕蛹是对人体健康有益的昆虫,不仅因其营养价值高,更重要的是食用时它们能发挥多种药理功能。目前,蚕蛹在药物应用方面备受关注。近年来,家蚕蛹的生物学功能逐渐得到鉴定和证实,尤其是对人体健康的有益作用。研究发现,蚕蛹对肝脏保护、免疫增强、抗凋亡、抗肿瘤、抗菌、调节血糖和血脂以及降低血压均有积极作用。然而,蚕蛹的药理机制和全身安全性尚未得到系统评估。本文首先总结了家蚕蛹的营养成分。然后对蚕蛹及其成分的药理功能进行分类,并描述其发生机制。此外,我们对蚕蛹的安全性进行了初步评估,分析了其应用前景,并为进一步的药理功能研究提出了未来方向。目的是激发人们对通过使用蚕蛹促进人类健康的兴趣。