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以家蚕(鳞翅目:蚕蛾科)为模型评估蚕桑产品及其降血糖作用

Products of Sericulture and Their Hypoglycemic Action Evaluated by Using the Silkworm, (Lepidoptera: Bombycidae), as a Model.

作者信息

Aznar-Cervantes Salvador D, Monteagudo Santesteban Beatriz, Cenis José L

机构信息

Departamento de Biotecnología, Genómica y Mejora Vegetal, Instituto Murciano de Investigación y Desarrollo Agrario y Medioambiental (IMIDA), La Alberca, 30150 Murcia, Spain.

出版信息

Insects. 2021 Nov 25;12(12):1059. doi: 10.3390/insects12121059.

Abstract

Sericulture generates different natural products with potential medical applications. Silk peptides, worms, or even pupae are commonly employed in traditional Asian medicine with a wide variety of purposes, and some scientific work has been focused on their antidiabetic properties. This work evaluates the postprandial antihyperglycemic activity of fibroin, sericin, and powder made from either larvae or pupae of silkworms, and L. (Lepidoptera: Bombycidae), employing the silkworm itself as an animal model. The results indicate a reduction in the glucose levels in hemolymph after sucrose or glucose-induced hyperglycemia when these products are included in the diet of the worms.

摘要

养蚕可生产出具有潜在医学应用价值的不同天然产物。丝肽、蚕体甚至蚕蛹在传统亚洲医学中被广泛用于多种用途,并且一些科学研究聚焦于它们的抗糖尿病特性。本研究以家蚕(鳞翅目:蚕蛾科)自身作为动物模型,评估了丝素蛋白、丝胶蛋白以及家蚕幼虫或蛹制成的粉末的餐后抗高血糖活性。结果表明,当将这些产品添加到家蚕的饮食中时,在蔗糖或葡萄糖诱导的高血糖症后,血淋巴中的葡萄糖水平会降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d641/8707728/caba172c7cd6/insects-12-01059-g001.jpg

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