Jóźwik Agnieszka, Przeździecka-Dołyk Joanna, Wałek Ewa, Czerniak Magdalena, Asejczyk Magdalena
Department of Optics and Photonics, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland.
Department of Ophthalmology, Wroclaw Medical University, Borowska 213, 50-556 Wrocław, Poland.
J Clin Med. 2022 May 24;11(11):2962. doi: 10.3390/jcm11112962.
Biomechanics of the cornea have significant influences on the non-contact measurement of the intraocular pressure. The corneal behaviour during tonometry is a fundamental factor in estimating its value. The aim of the study was to analyse the behaviour of the cornea during tonometric measurement with the forced change in intraocular pressure during the water drinking test. Ocular Response Analyser (Reichert) was used to the measurement. Besides four basic parameters connected with intraocular pressure (IOPg, IOPcc) and biomechanics (corneal hysteresis CH and corneal resistance factor (CRF), other parameters representing the behaviour of the cornea during a puff of air were analysed. There were 47 eyes included in the study, including 27 eyes with a XEN GelStent implanted and 20 without it. The eyes of people with monocular implementation were the reference group. The values of analysed parameters were compared before and after 10, 25, 40, and 55 min after drinking the water. The intraocular pressure increased by 2.4 mmHg (p < 0.05) for eyes with a XEN stent and 2.2 mmHg for eyes without a stent (p < 0.05) in the tenth minute after drinking of water. This change caused a decreasing of corneal hysteresis (p < 0.05) without significant changes in the corneal resistance factor (p > 0.05). Corneal hysteresis changed similarly in the reference group and the group with a XEN GelStent. The analysis of additional parameters showed a difference in the behaviour of the cornea in eyes with a XEN GelStent in comparison to the corneas of eyes without a stent. This was particularly visible in the analysis of the cornea’s behaviour during the second applanation, when the cornea returns to its baseline state after deformation caused by air puff tonometry.
角膜生物力学对眼压的非接触测量有重大影响。眼压测量过程中角膜的行为是估计眼压值的一个基本因素。本研究的目的是分析在饮水试验期间眼压强制变化时眼压测量过程中角膜的行为。使用眼反应分析仪（瑞奇德公司）进行测量。除了与眼压（眼压脉冲值、眼压补偿值）和生物力学（角膜滞后值和角膜阻力因子）相关的四个基本参数外，还分析了代表角膜在吹气时行为的其他参数。该研究纳入了47只眼睛，其中27只眼睛植入了XEN GelStent，20只未植入。单眼植入者的眼睛作为参照组。在饮水后10、25、40和55分钟前后比较分析参数的值。饮水后第10分钟，植入XEN支架的眼睛眼压升高2.4 mmHg（p<0.05），未植入支架的眼睛眼压升高2.2 mmHg（p<0.05）。这种变化导致角膜滞后值降低（p<0.05），而角膜阻力因子无显著变化（p>0.05）。参照组和植入XEN GelStent的组中角膜滞后值变化相似。对其他参数的分析显示，与未植入支架的眼睛的角膜相比，植入XEN GelStent的眼睛的角膜行为存在差异。这在第二次压平过程中角膜行为的分析中尤为明显，此时角膜在空气脉冲眼压测量引起的变形后恢复到基线状态。
