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预测、识别和治疗接受长期左心室辅助装置治疗患者的右心衰竭

Predicting, Recognizing, and Treating Right Heart Failure in Patients Undergoing Durable LVAD Therapy.

作者信息

Wang Teresa S, Cevasco Marisa, Birati Edo Y, Mazurek Jeremy A

机构信息

Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Division of Cardiovascular Surgery, Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

出版信息

J Clin Med. 2022 May 25;11(11):2984. doi: 10.3390/jcm11112984.

Abstract

Despite advancing technology, right heart failure after left ventricular assist device implantation remains a significant source of morbidity and mortality. With the UNOS allocation policy change, a larger proportion of patients proceeding to LVAD are destination therapy and consist of an overall sicker population. Thus, a comprehensive understanding of right heart failure is critical for ensuring the ongoing success of durable LVADs. The purpose of this review is to describe the effect of LVAD implantation on right heart function, review the diagnostic and predictive criteria related to right heart failure, and discuss the current evidence for management and treatment of post-LVAD right heart failure.

摘要

尽管技术不断进步,但左心室辅助装置植入术后的右心衰竭仍然是发病和死亡的重要原因。随着器官共享联合网络(UNOS)分配政策的改变,接受左心室辅助装置治疗的患者中,更大比例是接受目标治疗的,且总体病情更重。因此,全面了解右心衰竭对于确保长期左心室辅助装置的持续成功至关重要。本综述的目的是描述左心室辅助装置植入对右心功能的影响,回顾与右心衰竭相关的诊断和预测标准,并讨论目前左心室辅助装置植入术后右心衰竭管理和治疗的证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fa27/9181012/343f8032ff96/jcm-11-02984-g001.jpg

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