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49例青春期身高生长高峰后特发性脊柱侧凸患者椎体钉棒固定术:2-5年随访

Vertebral Body Tethering in 49 Adolescent Patients after Peak Height Velocity for the Treatment of Idiopathic Scoliosis: 2-5 Year Follow-Up.

作者信息

Meyers James, Eaker Lily, Zhang Jessica, di Pauli von Treuheim Theodor, Lonner Baron

机构信息

Department of Orthopaedic Surgery, Mount Sinai Hospital, New York, NY 10029, USA.

出版信息

J Clin Med. 2022 Jun 2;11(11):3161. doi: 10.3390/jcm11113161.

Abstract

Vertebral Body Tethering (VBT) is a non-fusion surgical treatment for Adolescent Idiopathic Scoliosis (AIS) that elicits correction via growth modulation in skeletally immature patients. VBT after peak height velocity is controversial and is the subject of this study. A retrospective review of Risser 3−5 AIS patients treated with VBT, and min. 2-year FU was performed. Pre to post-op changes in clinical outcomes were compared using Student’s t-test or the Mann-Whitney test. A total of 49 patients met criteria, age 15.0 ± 1.9 years, FU 32.5 ± 9.1 months. For thoracic (T) major curvatures, T curvature improved from 51.1 ± 6.9° to 27.2° ± 8.1° (p < 0.01) and TL from 37.2° ± 10.7° to 19.2° ± 6.8° (p < 0.01). For thoracolumbar (TL) major curvatures, T improved from 37.2° ± 10.7° to 18.8° ± 9.4° (p < 0.01) and TL from 49.0° ± 6.4° to 20.1° ± 8.5° (p < 0.01). Major curve inclinometer measurements and SRS-22 domains, except activity, improved significantly (p ≤ 0.05). At the latest FU, one (2%) patient required fusion of the T curve and revision of the TL tether due to curve progression in the previously uninstrumented T curve and tether breakage (TB) in the TL. Twenty (41%) patients experienced TB. VBT in AIS patients with limited remaining skeletal growth resulted in satisfactory clinical outcomes at the latest FU.

摘要

椎体牵张术(VBT)是一种针对青少年特发性脊柱侧凸(AIS)的非融合手术治疗方法,通过对骨骼未成熟患者的生长调节来实现矫正。高峰身高速度后进行VBT存在争议,也是本研究的主题。对接受VBT治疗且随访至少2年的Risser 3-5级AIS患者进行了回顾性研究。使用学生t检验或曼-惠特尼检验比较术前至术后临床结果的变化。共有49例患者符合标准,年龄15.0±1.9岁,随访32.5±9.1个月。对于胸段(T)主弯,T角从51.1±6.9°改善至27.2°±8.1°(p<0.01),胸腰段(TL)从37.2°±10.7°改善至19.2°±6.8°(p<0.01)。对于胸腰段主弯,T角从37.2°±10.7°改善至18.8°±9.4°(p<0.01),TL从49.0°±6.4°改善至20.1°±8.5°(p<0.01)。主要弯曲度测量仪测量结果和SRS-22量表各领域(除活动外)均有显著改善(p≤0.05)。在最近一次随访时,1例(2%)患者因之前未置入器械的T曲线进展和TL段牵索断裂(TB)而需要进行T曲线融合和TL牵索翻修。20例(41%)患者发生TB。对于剩余骨骼生长有限的AIS患者,VBT在最近一次随访时取得了满意的临床结果。

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