Vogl G, Pohl P, Willeit J, Aichner F
Digitale Bilddiagn. 1987 Mar;7(1):43-6.
An attempt was made to measure quantitatively the total cerebral blood flow by means of Duplex sonography. In a group of healthy young subjects a median value for total cerebral blood flow was obtained amounting to 469 ml/min +/- 30%; repeat measurements yielded a maximum deviation of +/- 11%. In three patients the values obtained after severe apoplectic insult due to occlusion of the internal carotid artery were definitely below the value of the group of healthy subjects, whereas the value for the total blood flow was in the upper range of normal values in a patient with occlusion of the a. cerebri media. Comparative measurements of the regional cerebral blood flow with xenon 133 yielded in those patients with occlusion of the internal carotid artery a markedly reduced mean flow and in the patient with occlusion of the a, cerebri media a less markedly reduced mean flow. Regionally reduced perfusion was seen in all the four patients in the range of the clinically and computer tomographically well-known ischaemia zone. Thanks to the simplicity of this sonographic examination method it could be a useful decision parameter in determining the indication for a reconstruction of the carotid artery, especially in asymptomatic patients.
尝试通过双功超声法定量测量全脑血流量。在一组健康年轻受试者中，获得的全脑血流量中位数为469毫升/分钟±30%；重复测量产生的最大偏差为±11%。在内侧颈内动脉闭塞导致严重中风损伤后的三名患者中，所获得的值明显低于健康受试者组的值，而大脑中动脉闭塞患者的全血流量值处于正常范围的上限。用氙133对局部脑血流量进行的对比测量显示，在内侧颈内动脉闭塞的患者中平均血流量明显降低，而在大脑中动脉闭塞的患者中平均血流量降低程度较小。在所有四名患者临床上和计算机断层扫描已知的缺血区域范围内均可见局部灌注减少。由于这种超声检查方法简单，它可能是确定颈动脉重建指征的有用决策参数，尤其是在无症状患者中。
