University of Health Sciences, Gaziosmanpaşa Taksim Training and Research Hospital, Department of Family Medicine & Occupational Health and Safety Clinic, İstanbul, Turkey.
Int J Clin Pract. 2022 Feb 21;2022:6065335. doi: 10.1155/2022/6065335. eCollection 2022.
This study aimed to determine the protection rates against hepatitis A virus (HAV) and hepatitis B virus (HBV), among healthcare providers (HCPs). The occupational health service data of Gaziosmanpaşa Training and Research Hospital between January 2020 and December 2020 were evaluated for this retrospective observational study. Of the 1,722 participants aged 34.40 ± 9.16 years, 48.6% ( = 861) were male, and 55.0% ( = 975) were doctors and nurses. The anti-HBs seropositivity rate was 87.5% ( = 1,501). None of the participants had anti-HCV antibodies. Twelve participants were HBsAg positive. A level of anti-HBs titer ≥10 mIU/mL was maintained in 66.7% of the HCPs vaccinated in childhood, while 71.3% ( = 1,263) of the participants had anti-HAV IgG. HAV vaccination needs were higher in the doctor and nurse groups than in the other groups (60.5% and 39.5%, respectively, = 0.003). HBV protection was higher among HCPs in polyclinics/wards and surgery/intensive care units than in those working in the emergency department (odds ratio (OR): 2.099, 95% confidence interval (CI) = 1.285-3.429; OR: 1.592, 95% CI = 1.037-2.443, respectively). HAV protection was higher in HCPs aged 31-50 years and over 50 years than in those aged 18-30 years (OR: 2.046, 95% CI = 1.647-2.541; OR: 3.615, 95% CI = 2.164-6.037, respectively). In this study, one out of every two HCPs aged 18-30 years admitted to the occupational health control services had not yet received the HAV vaccine. The low levels of HBV protection among HCPs in the emergency department highlight the need for occupational health screening and HBV vaccination for HCPs working in emergency services in hospitals.
这项研究旨在确定医疗机构工作人员(HCP)中甲型肝炎病毒(HAV)和乙型肝炎病毒(HBV)的保护率。对 2020 年 1 月至 12 月期间加济安泰普培训与研究医院的职业健康服务数据进行了回顾性观察研究。在 1722 名年龄为 34.40±9.16 岁的参与者中,48.6%(861 人)为男性,55.0%(975 人)为医生和护士。抗-HBs 血清阳性率为 87.5%(1501 人)。无丙型肝炎病毒抗体。12 名参与者 HBsAg 阳性。在儿童时期接种过疫苗的 HCP 中,66.7%(66.7%)保持了抗-HBs 滴度≥10mIU/mL,而 71.3%(1263 人)的参与者具有抗-HAV IgG。医生和护士组的 HAV 疫苗接种需求高于其他组(分别为 60.5%和 39.5%,=0.003)。与在急诊部门工作的 HCP 相比,在门诊部/病房和外科/重症监护病房工作的 HCP 中 HBV 保护率更高(比值比(OR):2.099,95%置信区间(CI):1.285-3.429;OR:1.592,95%CI:1.037-2.443)。31-50 岁和 50 岁以上的 HCP 中 HAV 保护率高于 18-30 岁的 HCP(OR:2.046,95%CI:1.647-2.541;OR:3.615,95%CI:2.164-6.037)。在这项研究中,每两名 18-30 岁的 HCP 中就有一人在接受职业健康控制服务时尚未接种 HAV 疫苗。急诊科 HCP 的 HBV 保护率较低,突出了医院急诊科 HCP 进行职业健康筛查和 HBV 疫苗接种的必要性。