Pain Management Unit, Department of Anaesthesia and Operating Theatre Services, Tuen Mun Hospital, Hong Kong.
Department of Anaesthesiology, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong.
Biomed Res Int. 2022 May 31;2022:2685898. doi: 10.1155/2022/2685898. eCollection 2022.
Knee osteoarthritis (KOA) is ubiquitous. However, effective pain managements for patients with grades 3 or 4 KOA for whom conservative treatments are unsuccessful, but for whom surgery is not an option, remain lacking. This case series presented two motor-sparing interventional pain treatment modalities for five such patients. Three of the patients with a mean total WOMAC score of 41 underwent thermal radiofrequency (RF) ablation using a modified motor-sparing approach. One-week and four-week post-RF, the total score dropped to 27 (by 34%) and 19 (dropped 53.7%), respectively. Two other similar patients with a mean total WOMAC score 96 underwent chemical neurolysis using a motor-sparing approach with modified landmarks. The WOMAC score dropped to 58.5 (by 39.1%) and 49 (dropped by 49.0%), one-week and four-week postchemical neurolysis, respectively. A narrative review of the currently available approaches is also provided, with the conclusion that neural ablation using the modified landmarks approach may achieve better pain control and preserve the motor functions for patients with severe KOA for whom conservative treatment was unsuccessful and who are not candidates for surgery.
膝骨关节炎(KOA)普遍存在。然而,对于那些保守治疗无效但又不能手术的 3 或 4 级 KOA 患者,仍缺乏有效的疼痛管理方法。本病例系列介绍了针对 5 名此类患者的两种保留运动的介入性疼痛治疗方法。3 名平均总 WOMAC 评分为 41 的患者接受了改良的保留运动的热射频(RF)消融。在 RF 后 1 周和 4 周,总评分分别降至 27(下降 34%)和 19(下降 53.7%)。另外 2 名类似的患者,平均总 WOMAC 评分为 96,采用改良标志的保留运动的化学神经溶解法。WOMAC 评分分别在化学神经溶解后 1 周和 4 周降至 58.5(下降 39.1%)和 49(下降 49.0%)。还对目前可用的方法进行了叙述性综述,结论是使用改良标志的神经消融方法可能为那些保守治疗无效且不能手术的严重 KOA 患者提供更好的疼痛控制和保留运动功能。