• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

足月新生儿因母亲接触卡比马唑导致腹裂

Gastroschisis Due to Maternal Exposure to Carbimazole in A Term Neonate.

作者信息

Asfour Suzan S, Al-Mouqdad Mountasser M

机构信息

Clinical Pharmacy Department, King Saud Medical City, Riyadh, SAU.

Neonatal Intensive Care Unit, King Saud Medical City, Riyadh, SAU.

出版信息

Cureus. 2022 May 7;14(5):e24808. doi: 10.7759/cureus.24808. eCollection 2022 May.

DOI:10.7759/cureus.24808
PMID:35686264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9170418/
Abstract

Pregnant women with hyperthyroidism need careful management, which is due to the increased risk of maternal and fetal complications. However, safe and effective therapies for hyperthyroidism during pregnancy remain limited. Carbimazole is an anti-thyroid agent and has been used to treat hyperthyroidism. Gastroschisis is a congenital severe abdominal birth defect of the fetus but its etiology remains unclear. Here, we present a case of a female term neonate who developed gastroschisis after being exposed to carbimazole in uteroduring the first and half of the second trimester.

摘要

患有甲状腺功能亢进症的孕妇需要仔细管理，这是因为母婴并发症的风险增加。然而，孕期甲状腺功能亢进症的安全有效治疗方法仍然有限。卡比马唑是一种抗甲状腺药物，一直用于治疗甲状腺功能亢进症。腹裂是胎儿先天性严重的腹部出生缺陷，但其病因尚不清楚。在此，我们报告一例足月女新生儿病例，该患儿在孕早期和孕中期前半期子宫内接触卡比马唑后发生了腹裂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1f/9170418/fd880e4613a3/cureus-0014-00000024808-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1f/9170418/6ddc0fea12e4/cureus-0014-00000024808-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1f/9170418/fd880e4613a3/cureus-0014-00000024808-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1f/9170418/6ddc0fea12e4/cureus-0014-00000024808-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e1f/9170418/fd880e4613a3/cureus-0014-00000024808-i02.jpg

相似文献

1
Gastroschisis Due to Maternal Exposure to Carbimazole in A Term Neonate.足月新生儿因母亲接触卡比马唑导致腹裂
Cureus. 2022 May 7;14(5):e24808. doi: 10.7759/cureus.24808. eCollection 2022 May.
2
Carbimazole-related gastroschisis.卡比马唑相关的腹裂
Ann Pharmacother. 2003 Jun;37(6):829-31. doi: 10.1345/aph.1C368.
3
Pharmacologic treatment of hyperthyroidism during pregnancy.妊娠期甲状腺功能亢进症的药物治疗。
Birth Defects Res A Clin Mol Teratol. 2012 Aug;94(8):612-9. doi: 10.1002/bdra.23012. Epub 2012 Apr 18.
4
Pregnancy with hyperthyroidism.甲亢合并妊娠
J Coll Physicians Surg Pak. 2003 May;13(5):255-9.
5
Challenges and lessons learnt in the management of an HIV-exposed neonate with gastroschisis in a resource-limited setting: case report.资源有限环境下一名患有腹裂的HIV暴露新生儿的管理挑战与经验教训：病例报告
Ann Med Surg (Lond). 2024 Mar 5;86(4):2208-2213. doi: 10.1097/MS9.0000000000001924. eCollection 2024 Apr.
6
Long-term assessment of children exposed in utero to carbimazole.对子宫内暴露于卡比马唑的儿童进行长期评估。
Arch Dis Child. 1976 Jul;51(7):532-6. doi: 10.1136/adc.51.7.532.
7
Anesthetic management of a neonate receiving prenatal repair of gastroschisis.接受产前腹裂修补术的新生儿的麻醉管理。
Int J Clin Exp Med. 2015 May 15;8(5):8234-7. eCollection 2015.
8
A case-control study of maternal periconceptual and pregnancy recreational drug use and fetal malformation using hair analysis.一项利用毛发分析对孕期及怀孕前后母亲使用消遣性药物与胎儿畸形进行的病例对照研究。
PLoS One. 2014 Oct 31;9(10):e111038. doi: 10.1371/journal.pone.0111038. eCollection 2014.
9
Treatment of hyperthyroidism in pregnancy.
Acta Obstet Gynecol Scand. 1991;70(6):461-3. doi: 10.3109/00016349109007160.
10
[Treatment of hyperthyroidism due to Graves' disease: what is the recommended antithyroid drug during pregnancy?].[格雷夫斯病所致甲状腺功能亢进的治疗：孕期推荐使用哪种抗甲状腺药物？]
J Gynecol Obstet Biol Reprod (Paris). 2013 May;42(3):232-7. doi: 10.1016/j.jgyn.2012.11.012. Epub 2013 Jan 9.

引用本文的文献

1
Effects of Methimazole vs Propylthiouracil in Newborns: A Comparative Review.甲巯咪唑与丙硫氧嘧啶对新生儿的影响：一项比较性综述。
Cureus. 2023 Jul 7;15(7):e41505. doi: 10.7759/cureus.41505. eCollection 2023 Jul.

本文引用的文献

1
Gastroschisis Following Treatment with High-Dose Methimazole in Pregnancy: A Case Report.孕期大剂量甲巯咪唑治疗后发生腹裂：1例报告
Drug Saf Case Rep. 2019 May 23;6(1):5. doi: 10.1007/s40800-019-0099-2.
2
Complexity of gastroschisis predicts outcome: epidemiology and experience in an Australian tertiary centre.复杂性先天性腹裂预测结局：澳大利亚一家三级中心的流行病学和经验。
BMC Pregnancy Childbirth. 2018 Jun 11;18(1):222. doi: 10.1186/s12884-018-1867-1.
3
Antithyroid Drugs and Congenital Malformations: A Nationwide Korean Cohort Study.
抗甲状腺药物与先天性畸形：一项全国性韩国队列研究。
Ann Intern Med. 2018 Mar 20;168(6):405-413. doi: 10.7326/M17-1398. Epub 2018 Jan 23.
4
2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis.2016年美国甲状腺协会甲状腺功能亢进症及其他甲状腺毒症病因的诊断和管理指南。
Thyroid. 2016 Oct;26(10):1343-1421. doi: 10.1089/thy.2016.0229.
5
Prevalence of thyrotoxicosis, antithyroid medication use, and complications among pregnant women in the United States.美国孕妇甲状腺功能亢进症、抗甲状腺药物使用及并发症的流行情况。
Thyroid. 2013 Jun;23(6):758-65. doi: 10.1089/thy.2012.0488.
6
Birth defects observed with maternal carbimazole treatment: Six cases reported to Nice's Pharmacovigilance Center.母体用卡比马唑治疗致出生缺陷：尼斯药物警戒中心报道六例。
Ann Endocrinol (Paris). 2010 Dec;71(6):535-42. doi: 10.1016/j.ando.2010.07.001. Epub 2010 Oct 12.
7
Management of Graves' hyperthyroidism in pregnancy: focus on both maternal and foetal thyroid function, and caution against surgical thyroidectomy in pregnancy.妊娠期格雷夫斯甲亢的管理：关注母体和胎儿的甲状腺功能，并警惕妊娠期手术甲状腺切除术。
Eur J Endocrinol. 2009 Jan;160(1):1-8. doi: 10.1530/EJE-08-0663. Epub 2008 Oct 10.
8
Development of gastroschisis: review of hypotheses, a novel hypothesis, and implications for research.腹裂的发生发展：假说综述、一种新假说及对研究的启示
Am J Med Genet A. 2007 Apr 1;143A(7):639-52. doi: 10.1002/ajmg.a.31578.
9
Carbimazole-related gastroschisis.卡比马唑相关的腹裂
Ann Pharmacother. 2003 Jun;37(6):829-31. doi: 10.1345/aph.1C368.
10
[Gastroschisis. Management. 50 cases].[腹裂。治疗。50例]
J Gynecol Obstet Biol Reprod (Paris). 1995;24(5):565-9.