足月新生儿因母亲接触卡比马唑导致腹裂
Gastroschisis Due to Maternal Exposure to Carbimazole in A Term Neonate.
作者信息
Asfour Suzan S, Al-Mouqdad Mountasser M
机构信息
Clinical Pharmacy Department, King Saud Medical City, Riyadh, SAU.
Neonatal Intensive Care Unit, King Saud Medical City, Riyadh, SAU.
出版信息
Cureus. 2022 May 7;14(5):e24808. doi: 10.7759/cureus.24808. eCollection 2022 May.
Abstract
Pregnant women with hyperthyroidism need careful management, which is due to the increased risk of maternal and fetal complications. However, safe and effective therapies for hyperthyroidism during pregnancy remain limited. Carbimazole is an anti-thyroid agent and has been used to treat hyperthyroidism. Gastroschisis is a congenital severe abdominal birth defect of the fetus but its etiology remains unclear. Here, we present a case of a female term neonate who developed gastroschisis after being exposed to carbimazole in uteroduring the first and half of the second trimester.
摘要
患有甲状腺功能亢进症的孕妇需要仔细管理，这是因为母婴并发症的风险增加。然而，孕期甲状腺功能亢进症的安全有效治疗方法仍然有限。卡比马唑是一种抗甲状腺药物，一直用于治疗甲状腺功能亢进症。腹裂是胎儿先天性严重的腹部出生缺陷，但其病因尚不清楚。在此，我们报告一例足月女新生儿病例，该患儿在孕早期和孕中期前半期子宫内接触卡比马唑后发生了腹裂。
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