Urology Department, UMAE, Hospital de Especialidades "Dr. Bernardo Sepúlveda Gutiérrez", IMSS, Ciudad de México, México.
Neuro-Urology Department, Moinhos de Vento Hospital, Porto Alegre, Brazil.
Neurourol Urodyn. 2022 Aug;41(6):1248-1257. doi: 10.1002/nau.24982. Epub 2022 Jun 10.
To summarize available data focused on diagnosis and management of urethral stricture in men with neurogenic lower urinary tract dysfunction by a systematic review of the literature.
A systematic review of the literature was carried out through an extensive electronic database search performed in PubMed/MEDLINE and Scopus databases for full texts, and International Continence Society, American Urology Association, and European Association of Urology abstracts for citations related to urethral structure. This review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis.
A total of 316 articles were identified, 48 of which were selected for this review. Different strategies are currently being used for the management of urethral strictures, such as clean intermittent catheterization (CIC) which reduces stricture by up to 68%; direct vision internal urethrotomy which shows lower rates of renarrowing; urethroplasty which shows a success rate up to 70%; urinary diversion is the treatment of choice when reconstruction is not possible.
Further studies are needed in this population because of the heterogeneity of the outcomes and the lack of a standardized definition and classification of this population.
通过对文献进行系统回顾，总结目前有关神经源性下尿路功能障碍男性尿道狭窄的诊断和治疗的可用数据。
通过在 PubMed/MEDLINE 和 Scopus 数据库中进行广泛的电子数据库搜索，以及对国际尿控协会、美国泌尿科协会和欧洲泌尿科协会的引用进行分析，对文献进行了系统回顾，以获取与尿道结构相关的全文和摘要。本综述按照系统评价和荟萃分析的首选报告项目进行。
共确定了 316 篇文章，其中 48 篇被选入本综述。目前，尿道狭窄的治疗策略有很多种，如清洁间歇性导尿（CIC），可以将狭窄减少多达 68%；直接视线下尿道内切开术显示狭窄再狭窄率较低；尿道成形术的成功率高达 70%；当重建不可能时，尿流改道是首选治疗方法。
由于该人群的结果存在异质性，且缺乏对该人群的标准化定义和分类，因此需要进一步研究。
