Nebes R D, Boller F
Cortex. 1987 Mar;23(1):87-98. doi: 10.1016/s0010-9452(87)80021-7.
Recent findings suggest that some components of semantic memory are spared by Alzheimer's disease. The present study used a visual-search task to determine whether knowledge of the sequential letter dependencies present in spelling remains intact in demented patients. The speed with which twenty Alzheimer patients, twenty young and twenty old controls searched an array of letters for a target was measured. Arrays varied in how closely they approximated English-spelling patterns (zero-order, and third-order approximations and actual words). Despite differing in their overall speed of response, normal and demented subjects were affected equally by the approximation to English of the stimuli (i.e., both searched words faster than low-order approximations). Thus, knowledge of the probability patterns of spelling appears to remain intact and accessible in the semantic memory of demented patients.
最近的研究结果表明，语义记忆的某些成分在阿尔茨海默病中未受影响。本研究采用视觉搜索任务来确定痴呆患者对拼写中存在的连续字母依存关系的了解是否仍然完好。测量了20名阿尔茨海默病患者、20名年轻对照者和20名老年对照者在一系列字母中搜索目标的速度。数组在接近英语拼写模式的程度上有所不同（零阶、三阶近似和实际单词）。尽管正常受试者和痴呆受试者的总体反应速度不同，但刺激与英语的近似程度对他们的影响是相同的（即，两者搜索单词的速度都比低阶近似更快）。因此，拼写概率模式的知识在痴呆患者的语义记忆中似乎仍然完好且可及。
