Department of Cardiovascular Surgery, University Heart and Vascular Center UKE Hamburg, Hamburg, Germany.
Department of Cardiothoracic Surgery, Augsburg University Hospital, Augsburg, Germany.
J Card Surg. 2022 Sep;37(9):2734-2737. doi: 10.1111/jocs.16683. Epub 2022 Jun 11.
We evaluated the potential of cardiac magnetic resonance (CMR)-derived strain to assess aortic valve (AV) annulus deformation during the cardiac cycle in regurgitant and well-functioning AVs.
Four patients with severe aortic regurgitation and seven healthy controls underwent CMR. Assessment of longitudinal strain was performed by hypothesizing the AV annulus would be the left ventricle in long-axis orientation. Longitudinal strain of the segments belonging to the muscular and fibrous AV annulus was weighted and averaged to obtain regional values (RLS).
Comparison of RLS between regurgitant and well-functioning AVs showed a considerably different deformation of the muscular AV annulus (i.e., median RLS: 4.18 % [patients] vs. -10.41 % [controls], p = .024). The fibrous AV annulus demonstrated comparable deformational changes in both groups.
CMR-derived strain allows for quantification of AV annulus deformation during the cardiac cycle and shows an altered RLS in the muscular AV annulus in patients with severe aortic regurgitation.
我们评估心脏磁共振（CMR）衍生应变在心脏周期中评估反流和功能良好的主动脉瓣（AV）瓣环变形的潜力。
4 例严重主动脉瓣反流患者和 7 例健康对照者接受 CMR 检查。通过假设 AV 瓣环在长轴方向上是左心室，来评估纵向应变。加权并平均属于肌肉和纤维性 AV 瓣环的节段的纵向应变以获得区域值（RLS）。
比较反流和功能良好的 AVs 之间的 RLS，显示肌肉性 AV 瓣环的变形明显不同（即，中位数 RLS：4.18％[患者]与-10.41％[对照组]，p = .024）。两组的纤维性 AV 瓣环显示出可比的变形变化。
CMR 衍生的应变允许量化心脏周期中 AV 瓣环的变形，并显示出严重主动脉瓣反流患者中肌肉性 AV 瓣环的 RLS 改变。
