BCG 膀胱内灌注后引起的真菌性动脉性动脉瘤：综述。
Mycotic arterial aneurysm secondary to BCG intravesical instillation: A review.
机构信息
Department of vascular surgery, Rouen university hospital, 1, rue de Germont, 76031 Rouen cedex, France.
Department of vascular surgery, Rouen university hospital, 1, rue de Germont, 76031 Rouen cedex, France.
出版信息
J Med Vasc. 2022 Apr;47(2):94-105. doi: 10.1016/j.jdmv.2022.04.002. Epub 2022 May 20.
OBJECTIVE
Mycotic aortic aneurysm is a rare and life-threatening pathology. The first case of mycotic aneurysm induced by immunotherapy with bacille Calmette-Guérin for malignancy was published in 1988. The main objective of this review is to characterize this rare pathology.
MATERIALS AND METHODS
Since then, 60 cases of arterial aneurysm following intra vesical BCG instillation have been described in the literature. All cases have been included, and characteristics have been collected retrospectively, with simple statistical analyses of the cases.
RESULTS
We present a brief review from 1988 to 2022 enhancing the contemporary understanding of this arterial infection. Mycotic aneurysm secondary to BCG instillation has a poor prognosis, up to 50% complication and 15% mortality at 1 month, whether managed by open repair or endovascular means.
CONCLUSION
BCG mycotic aneurysm is an extremely serious condition, the diagnosis of which must be considered at an early stage in order to adapt diagnostic and therapeutic strategies.
目的
感染性主动脉瘤是一种罕见且危及生命的疾病。1988 年首次报道了恶性肿瘤使用卡介苗免疫治疗引起感染性主动脉瘤的病例。本研究的主要目的是描述这种罕见的病理。
材料和方法
自那时以来，文献中已经描述了 60 例经膀胱内 BCG 灌注后发生的动脉性动脉瘤。所有病例均被纳入，并回顾性地收集特征，对病例进行简单的统计分析。
结果
我们对 1988 年至 2022 年的文献进行了简要回顾，加深了对这种动脉感染的当代认识。BCG 灌注后引起的感染性动脉瘤预后不良，无论采用开放修复还是血管内治疗，1 个月时并发症发生率高达 50%，死亡率为 15%。
结论
BCG 感染性动脉瘤是一种极其严重的疾病，必须早期诊断，以便调整诊断和治疗策略。
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