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2022 年骨质疏松症:从护理差距到筛查和个体化医学。

Osteoporosis in 2022: Care gaps to screening and personalised medicine.

机构信息

MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton General Hospital, Southampton, UK.

MRC Lifecourse Epidemiology Centre, University of Southampton, Southampton General Hospital, Southampton, UK; NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospitals Southampton NHS Foundation Trust, Southampton, UK; NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.

出版信息

Best Pract Res Clin Rheumatol. 2022 Sep;36(3):101754. doi: 10.1016/j.berh.2022.101754. Epub 2022 Jun 9.

Abstract

Osteoporosis care has evolved markedly over the last 50 years, such that there are now an established clinical definition, validated methods of fracture risk assessment, and a range of effective pharmacological agents. However, it is apparent that both in the context of primary and secondary fracture prevention, there is a considerable gap between the population at high fracture risk and those actually receiving appropriate antiosteoporosis treatment. In this narrative review article, we document recent work describing the burden of disease, approaches to management, and service provision across Europe, emerging data on gaps in care, and existing/new ways in which these gaps may be addressed at the level of healthcare systems and policy. We conclude that although the field has come a long way in recent decades, there is still a long way to go, and a concerted, integrated effort is now required from all of us involved in this field to address these urgent issues to ensure the best possible outcomes for our patients.

摘要

在过去的 50 年中,骨质疏松症的治疗发生了显著的变化,现在已经有了明确的临床定义、经过验证的骨折风险评估方法以及一系列有效的药物治疗方法。然而,在原发性和继发性骨折预防方面,高骨折风险人群与实际接受适当抗骨质疏松症治疗的人群之间显然存在相当大的差距。在这篇叙述性综述文章中,我们记录了最近的工作,描述了欧洲的疾病负担、管理方法和服务提供情况,以及关于护理差距的新兴数据,以及在医疗保健系统和政策层面上可能解决这些差距的现有/新方法。我们得出结论,尽管该领域在最近几十年取得了长足的进步,但仍有很长的路要走,我们所有参与这一领域的人都需要齐心协力,共同努力,解决这些紧迫的问题,以确保为我们的患者提供最佳的治疗效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a498/7614114/6d96161702db/EMS146100-f001.jpg

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