Ueda Takashi, Mori Hideki, Sekiguchi Tatsuya, Mishima Yusuke, Sano Masaya, Teramura Erika, Fujimoto Ryutaro, Kaneko Motoki, Nakae Hirohiko, Fujisawa Mia, Matsushima Masashi, Suzuki Hidekazu
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Kanagawa 259-1193, Japan.
Translational Research Center for Gastrointestinal Disorders (TARGID), University of Leuven, Leuven 3000, Belgium.
J Clin Biochem Nutr. 2022 May;70(3):283-289. doi: 10.3164/jcbn.21-123. Epub 2021 Nov 26.
Transarterial embolization (TAE) is performed in patients with colonic diverticular bleeding after difficult endoscopic hemostasis or rebleeding. A total of 375 patients with hematochezia at our hospital from 1 April 2016 to 31 March 2020 were retrospectively analysed. Firstly, we compared the group in which hemostasis was achieved by endoscopy alone with the group that eventually underwent TAE. Secondly, we compared the group in which hemostasis was achieved by endoscopy alone, with the group switched to TAE after endoscopic hemostasis failed. The group that eventually underwent TAE had a higher shock index and lower Alb and PT% than the endoscopic hemostasis group. The shock index was correlated with Alb and PT%. When the cut-off value for the shock index was defined as more than 0.740, an OR of 9.500, a positive predictive value (PPV) of 40.0%, a negative predictive value (NPV) of 93.4%, and an accuracy of 80.3% were obtained for predicting a switch to TAE treatment. The greatest risk for TAE was the presence of shock and extravasation on contrast-enhanced CT. A switch to TAE treatment was likely when the shock index was more than 0.740. TAE should be considered in cases with a high shock index and showing extravasation on contrast-enhanced CT.
对于经内镜止血困难或再次出血的结肠憩室出血患者,需进行经动脉栓塞术(TAE)。对2016年4月1日至2020年3月31日期间我院收治的375例便血患者进行回顾性分析。首先,我们将单纯经内镜止血成功的患者组与最终接受TAE的患者组进行比较。其次,我们将单纯经内镜止血成功的患者组与内镜止血失败后转而接受TAE的患者组进行比较。最终接受TAE的患者组的休克指数高于内镜止血组,白蛋白(Alb)和凝血酶原百分比(PT%)低于内镜止血组。休克指数与Alb和PT%相关。当休克指数的截断值定义为大于0.740时,预测转为TAE治疗的比值比(OR)为9.500,阳性预测值(PPV)为40.0%,阴性预测值(NPV)为93.4%,准确率为80.3%。TAE的最大风险是增强CT上出现休克和造影剂外渗。当休克指数大于0.740时,可能需要转为TAE治疗。对于休克指数高且增强CT显示造影剂外渗的病例,应考虑TAE治疗。