• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

左侧瓣膜性心脏病患者的干预时机与方式：个体化方法

Timing and mode of intervention for patients with left sided valvular heart disease: an individualized approach.

作者信息

McConkey Hannah, Zhao Zhengang, Redwood S, Chen M, Prendergast B D

机构信息

King's College London British Heart Foundation Centre of Excellence, The Rayne Institute, St. Thomas' Hospital Campus, London, United Kingdom, and the Department of Cardiology, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom.

Department of Cardiology, West China Hospital, Sichuan University.

出版信息

Precis Clin Med. 2018 Dec;1(3):118-128. doi: 10.1093/pcmedi/pby017. Epub 2018 Dec 19.

DOI:10.1093/pcmedi/pby017
PMID:35692702
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8985789/
Abstract

Left sided valvular heart disease poses major impact on life and lifestyle. Medical therapy merely palliates chronic severe valve disease and once symptoms or haemodynamic sequelae appear, life expectancy is markedly truncated. In this article, we review the mechanisms of valve pathology, latest evidence in the quest for pharmacological options, means by which to predict deterioration, and standard and novel treatment options.

摘要

左侧心脏瓣膜病对生活及生活方式有重大影响。药物治疗仅能缓解慢性重症瓣膜病，一旦出现症状或血流动力学后遗症，预期寿命会显著缩短。在本文中，我们综述了瓣膜病理机制、寻找药物治疗方案的最新证据、预测病情恶化的方法以及标准和新型治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91ae/8985789/b1b3de11dfa1/pby017f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91ae/8985789/8882ef0eb81a/pby017f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91ae/8985789/b1b3de11dfa1/pby017f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91ae/8985789/8882ef0eb81a/pby017f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91ae/8985789/b1b3de11dfa1/pby017f02.jpg

相似文献

1
Timing and mode of intervention for patients with left sided valvular heart disease: an individualized approach.左侧瓣膜性心脏病患者的干预时机与方式：个体化方法
Precis Clin Med. 2018 Dec;1(3):118-128. doi: 10.1093/pcmedi/pby017. Epub 2018 Dec 19.
2
Tricuspid regurgitation: Frequency, clinical presentation, management and outcome among patients with severe left-sided valvular heart disease in Europe. Insights from the ESC-EORP Valvular Heart Disease II survey.三尖瓣反流：欧洲重度左侧瓣膜性心脏病患者的发生率、临床表现、管理及预后。欧洲心脏病学会-欧洲注册瓣膜性心脏病II调查的见解
Eur J Heart Fail. 2024 Apr;26(4):994-1003. doi: 10.1002/ejhf.3157. Epub 2024 Feb 19.
3
Impact of Right-Sided-Catheter-Based Valve Implantation on Decision-Making in Congenital Heart Disease.基于右侧导管的瓣膜植入对先天性心脏病决策的影响。
Curr Cardiol Rep. 2016 Apr;18(4):33. doi: 10.1007/s11886-016-0712-2.
4
Timing of intervention in asymptomatic patients with valvular heart disease.无症状瓣膜性心脏病患者的干预时机。
Eur Heart J. 2020 Dec 1;41(45):4349-4356. doi: 10.1093/eurheartj/ehaa485.
5
Effect of oral anticoagulation on clinical outcomes and haemodynamic variables after successful transcatheter aortic valve implantation.经导管主动脉瓣置换术后口服抗凝对临床结局和血流动力学变量的影响。
Arch Cardiovasc Dis. 2020 May;113(5):341-349. doi: 10.1016/j.acvd.2019.12.008. Epub 2020 Feb 27.
6
Management of valvular heart disease in the pregnant patient.妊娠期瓣膜性心脏病的处理。
Expert Rev Cardiovasc Ther. 2020 Aug;18(8):495-501. doi: 10.1080/14779072.2020.1797490. Epub 2020 Jul 27.
7
[Congenital heart disease and acquired valvular lesions in pregnancy].[妊娠期先天性心脏病与获得性瓣膜病变]
Herz. 2003 May;28(3):227-39. doi: 10.1007/s00059-003-2467-y.
8
Characteristics, management, and outcomes of patients with multiple native valvular heart disease: a substudy of the EURObservational Research Programme Valvular Heart Disease II Survey.多瓣膜心脏疾病患者的特征、治疗和结局：EURObservational Research Programme Valvular Heart Disease II 调查的一项子研究。
Eur Heart J. 2022 Aug 1;43(29):2756-2766. doi: 10.1093/eurheartj/ehac209.
9
Contemporary Presentation and Management of Valvular Heart Disease: The EURObservational Research Programme Valvular Heart Disease II Survey.当代瓣膜性心脏病的表现与处理：EURObservational Research Programme-Valvular Heart Disease II 调查。
Circulation. 2019 Oct;140(14):1156-1169. doi: 10.1161/CIRCULATIONAHA.119.041080. Epub 2019 Sep 12.
10
Update on Valvular Heart Disease in Pregnancy.妊娠期间瓣膜性心脏病的最新进展
Curr Treat Options Cardiovasc Med. 2017 Sep;19(9):70. doi: 10.1007/s11936-017-0570-2.

引用本文的文献

1
Radiotherapy-induced heart disease: a review of the literature.放射治疗诱发的心脏病：文献综述
Precis Clin Med. 2019 Dec;2(4):270-282. doi: 10.1093/pcmedi/pbz025. Epub 2019 Nov 29.
2
Computational modeling of cardiac growth and remodeling in pressure overloaded hearts-Linking microstructure to organ phenotype.计算模型研究压力超负荷心脏中的心脏生长和重构——将微观结构与器官表型联系起来。
Acta Biomater. 2020 Apr 1;106:34-53. doi: 10.1016/j.actbio.2020.02.010. Epub 2020 Feb 11.

本文引用的文献

1
Transcatheter Mitral-Valve Repair in Patients with Heart Failure.经导管二尖瓣修复术治疗心力衰竭患者。
N Engl J Med. 2018 Dec 13;379(24):2307-2318. doi: 10.1056/NEJMoa1806640. Epub 2018 Sep 23.
2
Association of Left Ventricular Global Longitudinal Strain With Asymptomatic Severe Aortic Stenosis: Natural Course and Prognostic Value.左心室整体纵向应变与无症状严重主动脉瓣狭窄的相关性：自然病程和预后价值。
JAMA Cardiol. 2018 Sep 1;3(9):839-847. doi: 10.1001/jamacardio.2018.2288.
3
Timing of intervention in aortic stenosis: a review of current and future strategies.
主动脉瓣狭窄的干预时机：当前及未来策略综述
Heart. 2018 Dec;104(24):2067-2076. doi: 10.1136/heartjnl-2017-312304. Epub 2018 Jul 20.
4
Transfemoral Implantation of the Acurate neo for the Treatment of Aortic Regurgitation.经股动脉植入Acurate neo治疗主动脉瓣反流
J Invasive Cardiol. 2018 Sep;30(9):329-333. Epub 2018 Jul 15.
5
Myocardial Strain in Prediction of Outcomes After Surgery for Severe Mitral Regurgitation.心肌应变预测重度二尖瓣反流手术后结局。
JACC Cardiovasc Imaging. 2018 Sep;11(9):1235-1244. doi: 10.1016/j.jcmg.2018.03.016. Epub 2018 May 16.
6
1-Year Outcomes of Transcatheter Mitral Valve Replacement in Patients With Severe Mitral Annular Calcification.经导管二尖瓣置换术治疗重度二尖瓣环钙化患者的 1 年结果。
J Am Coll Cardiol. 2018 May 1;71(17):1841-1853. doi: 10.1016/j.jacc.2018.02.054.
7
Mitral Valve Regurgitation in the Contemporary Era: Insights Into Diagnosis, Management, and Future Directions.当代二尖瓣反流：诊断、治疗和未来方向的新见解。
JACC Cardiovasc Imaging. 2018 Apr;11(4):628-643. doi: 10.1016/j.jcmg.2018.01.009.
8
Transcatheter Aortic Valve Replacement in Pure Native Aortic Valve Regurgitation.经导管主动脉瓣置换术治疗单纯性主动脉瓣反流。
J Am Coll Cardiol. 2017 Dec 5;70(22):2752-2763. doi: 10.1016/j.jacc.2017.10.006.
9
Early Experience With New Transcatheter Mitral Valve Replacement.新型经导管二尖瓣置换术的早期经验。
J Am Coll Cardiol. 2018 Jan 2;71(1):12-21. doi: 10.1016/j.jacc.2017.10.061. Epub 2017 Nov 16.
10
Reappraising myocardial fibrosis in severe aortic stenosis: an invasive and non-invasive study in 133 patients.重新评估严重主动脉瓣狭窄中的心肌纤维化：133 例患者的一项侵袭性和非侵袭性研究。
Eur Heart J. 2018 Feb 21;39(8):699-709. doi: 10.1093/eurheartj/ehx353.