Xu Binbin, Hu Li, Cheng Qinqin, K W So Winnie
The Nethersole School of Nursing, The Chinese University of Hong Kong, Hong Kong SAR, China.
Breast Surgical Department, The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Asia Pac J Oncol Nurs. 2022 Apr 27;9(8):100071. doi: 10.1016/j.apjon.2022.04.010. eCollection 2022 Aug.
Financial toxicity (FT) has been used to describe patients' whole economic experience that negatively impacts their well-being. FT's adverse effects on patients' health outcomes have been reported by reviews conducted in Western countries. However, these findings may not apply to patients in China. This review aimed to analyze existing data on the measures, prevalence, risk factors, and health-related consequences of FT in China. We searched 10 databases in May 2021 and again in January 2022 using Medical Subject Headings terms and free text. We also searched the reference lists of included articles. Two reviewers independently screened the studies, extracted the data, and assessed the quality of the included studies using the Joanna Briggs Institute Critical Appraisal Checklist. Thirty-one articles describing 30 studies were included in the analysis. Various FT measures were identified, but the number of validated measures was limited. The prevalence of material, psychological, and behavioral FT was 6%-78%, 61%-84%, and 10%-79%, respectively. We identified common risk factors and health-related consequences associated with FT similar to those reported in previous reviews. We also identified several potential risk factors (eg, increased length of hospital stay and larger household size) and consequences (patients' self-perceived burden) in a limited number of studies. Our findings show an urgent need for more data on the prevalence, risk factors, and health-related consequences associated with FT in Chinese cancer patients, and these data must be generated using validated measures.
经济毒性（FT）已被用于描述对患者幸福感产生负面影响的整体经济体验。西方国家进行的综述报告了FT对患者健康结局的不利影响。然而，这些研究结果可能不适用于中国患者。本综述旨在分析中国FT在测量方法、患病率、危险因素及与健康相关后果方面的现有数据。我们于2021年5月及2022年1月使用医学主题词和自由文本检索了10个数据库。我们还检索了纳入文章的参考文献列表。两名评审员独立筛选研究、提取数据，并使用乔安娜·布里格斯研究所的批判性评价清单评估纳入研究的质量。分析纳入了31篇描述30项研究的文章。确定了各种FT测量方法，但经过验证的测量方法数量有限。物质性、心理性和行为性FT的患病率分别为6% - 78%、61% - 84%和10% - 79%。我们确定了与FT相关的常见危险因素及与健康相关的后果，与之前综述中报告的相似。我们还在少数研究中确定了几个潜在危险因素（如住院时间延长和家庭规模较大）及后果（患者自我感知的负担）。我们的研究结果表明，迫切需要更多关于中国癌症患者FT患病率、危险因素及与健康相关后果的数据，且这些数据必须使用经过验证的测量方法来生成。
