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内镜检查中的质量指标:对证据总体科学水平及利益冲突的系统分析

Quality measures in endoscopy: A systematic analysis of the overall scientific level of evidence and conflicts of interest.

作者信息

Weissman Simcha, Aziz Muhammad, Baniqued Matthew R, Taneja Vikas, El-Dallal Mohammed, Lee-Smith Wade, Elias Sameh, Feuerstein Joseph D

机构信息

Department of Medicine, Hackensack Meridian Health Palisades Medical Center, North Bergen, New Jersey, United States.

Division of Gastroenterology and Hepatology, University of Toledo Medical Center, Toledo, Ohio, United States.

出版信息

Endosc Int Open. 2022 Jun 10;10(6):E776-E786. doi: 10.1055/a-1809-4219. eCollection 2022 Jun.

Abstract

Quality measures were established to develop standards to help assess quality of care, yet variation in endoscopy exists. We performed a systematic review to assess the overall quality of evidence cited in formulating quality measures in endoscopy. A systematic search was performed on multiple databases from inception until November 15, 2020, to examine the quality measures proposed by all major societies. Quality measures were assessed for their level of quality evidence and categorized as category A (guideline-based), category B (observational studies) or category C (expert opinion). They were also examined for the type of measure (process, structure, outcome), the quality, measurability, review, existing conflicts of interest (COI), and patient participation of the quality measure. An aggregate total of 214 quality measures from nine societies (15 manuscripts) were included and analyzed. Of quality measures in endoscopy, 71.5 %, 23.8 %, and 4.7 % were based on low, moderate, and high quality of evidence, respectively. The proportion of high-quality evidence across societies was significantly different (  = 0.028). Of quality measures, 76 % were quantifiable, 18 % contained patient-centric outcomes, and 7 % reported outcome measures. None of the organizations reported on patient involvement or external review, six disclosed existing COI, and 40 % were published more than 5 years ago. Quality measures are important to standardize clinical practice. Because over 70 % of quality measures in endoscopy are based on low-quality evidence, further studies are needed to improve the overall quality to effectively set a standard, reduce variation, and improve care in endoscopic practice.

摘要

已制定质量指标以制定标准,帮助评估医疗质量,但内镜检查仍存在差异。我们进行了一项系统评价,以评估在内镜检查质量指标制定过程中所引用证据的整体质量。对多个数据库从建库至2020年11月15日进行了系统检索,以审查所有主要学会提出的质量指标。对质量指标的质量证据水平进行评估,并分为A类(基于指南)、B类(观察性研究)或C类(专家意见)。还对质量指标的类型(过程、结构、结果)、质量、可测量性、审查、现有利益冲突(COI)以及患者参与情况进行了审查。总共纳入并分析了来自9个学会的214项质量指标(15篇手稿)。在内镜检查质量指标中,分别有71.5%、23.8%和4.7%基于低质量、中等质量和高质量证据。各学会间高质量证据的比例存在显著差异(P = 0.028)。在质量指标中,76%是可量化的,18%包含以患者为中心的结果,7%报告了结果指标。没有组织报告患者参与情况或外部审查,6个组织披露了现有利益冲突,40%是5年多以前发表的。质量指标对于规范临床实践很重要。由于内镜检查中超过70%的质量指标基于低质量证据,需要进一步研究以提高整体质量,从而有效设定标准、减少差异并改善内镜检查实践中的医疗服务。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/260d/9187391/f60ef37fb128/10-1055-a-1809-4219-i2482ei1.jpg

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