Almannaei Lulwa, Alsaadoon Ebrahim, AlbinAli Sultan, Taha Mohammed, Lambert Imelda
Pediatrics Department, King Hamad University Hospital, Busaiteen, Bahrain.
Access Microbiol. 2022 Mar 21;4(3):000332. doi: 10.1099/acmi.0.000332. eCollection 2022.
Respiratory tract infections are a leading cause of hospital visits in the paediatric population and carry significant associated morbidity and mortality in this population. The introduction of respiratory panel testing has been said to guide clinicians in the overall management of patients. We conducted a retrospective study examining all respiratory panels carried out in our hospital during 2019 on paediatric patients. Patients included were those who had symptoms indicative of respiratory infections who presented acutely, including those with chronic respiratory conditions. A total of 188 respiratory panel results were obtained along with collected patient data. These were analysed using SPSS V. 25.0 to get the below mentioned results. The majority (76.6 %) of patients were less than 3 years with 59 % of total population being males. The majority (80.9 %) had mild clinical severity score. The most common pathogen that was detected on the respiratory panel was spp, followed by the viruses. Only four cases were positive for bacterial pathogens (two , one and one ), which accounts for 2.1 % of all panels analysed. The significance of respiratory panels in influencing treatment were analysed in the forms of change of management plans before and after results of respiratory panels. This was observed in 14.4 % of patients who were not on any empiric medication and then based on panel results were started on medications, as well as 11.7 % who were on medications already, and the medications were altered based on the result of the panel (Chi square =0.057). This was mainly seen with cases of patients and to a lesser extent, . The use of respiratory panels in our hospital had little impact on patient care and management. The main organisms that influenced clinician decision in treatment were viruses and bacterial organisms ( , and ). Other than that, the use of clinical judgement proved more beneficial. We recommend use of specific testing for these organisms rather than the whole panel as case to case bases, which would be more cost-effective and consistent with patient management.
呼吸道感染是儿科人群住院就诊的主要原因，且在该人群中伴有显著的发病和死亡情况。据说引入呼吸道病原体检测组合有助于指导临床医生对患者进行全面管理。我们进行了一项回顾性研究，调查了2019年在我院对儿科患者进行的所有呼吸道病原体检测组合情况。纳入的患者为急性出现呼吸道感染症状者，包括患有慢性呼吸道疾病的患者。共获得188份呼吸道病原体检测组合结果以及收集的患者数据。使用SPSS V. 25.0对这些数据进行分析，得出以下结果。大多数（76.6%）患者年龄小于3岁，男性占总人口的59%。大多数（80.9%）患者临床严重程度评分为轻度。呼吸道病原体检测组合中检测到的最常见病原体是 spp，其次是 病毒。仅4例细菌性病原体检测呈阳性（2例 ，1例 和1例 ），占所有分析检测组合的2.1%。通过呼吸道病原体检测组合结果前后管理计划的变化形式，分析了呼吸道病原体检测组合对治疗的影响。在14.4%未接受任何经验性用药的患者中观察到这种情况，基于检测组合结果开始用药，以及11.7%已在用药的患者中，根据检测组合结果改变了用药（卡方检验=0.057）。这主要见于 患者，在 患者中程度较轻。我院使用呼吸道病原体检测组合对患者护理和管理影响不大。影响临床医生治疗决策的主要病原体是 病毒和细菌性病原体（ 、 和 ）。除此之外，临床判断的使用被证明更有益。我们建议根据具体病例对这些病原体进行针对性检测，而不是进行整个检测组合，这样更具成本效益且与患者管理一致。
