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神经性厌食症和强迫症中执行功能的神经关联

Neural Correlates of Executive Functioning in Anorexia Nervosa and Obsessive-Compulsive Disorder.

作者信息

Thomas Kai S, Birch Rosalind E, Jones Catherine R G, Vanderwert Ross E

机构信息

School of Psychology, Cardiff University, Cardiff, United Kingdom.

Cardiff University Centre for Human Developmental Science, School of Psychology, Cardiff University, Cardiff, United Kingdom.

出版信息

Front Hum Neurosci. 2022 May 26;16:841633. doi: 10.3389/fnhum.2022.841633. eCollection 2022.

Abstract

Anorexia nervosa (AN) and obsessive-compulsive disorder (OCD) are commonly reported to co-occur and present with overlapping symptomatology. Executive functioning difficulties have been implicated in both mental health conditions. However, studies directly comparing these functions in AN and OCD are extremely limited. This review provides a synthesis of behavioral and neuroimaging research examining executive functioning in AN and OCD to bridge this gap in knowledge. We outline the similarities and differences in behavioral and neuroimaging findings between AN and OCD, focusing on set shifting, working memory, response inhibition, and response monitoring. This review aims to facilitate understanding of transdiagnostic correlates of executive functioning and highlights important considerations for future research. We also discuss the importance of examining both behavioral and neural markers when studying transdiagnostic correlates of executive functions.

摘要

神经性厌食症(AN)和强迫症(OCD)通常被报道会同时出现且症状重叠。执行功能困难在这两种心理健康状况中都有涉及。然而,直接比较AN和OCD中这些功能的研究极其有限。本综述综合了行为和神经影像学研究,以检验AN和OCD中的执行功能,从而弥补这一知识空白。我们概述了AN和OCD在行为和神经影像学研究结果上的异同,重点关注任务转换、工作记忆、反应抑制和反应监测。本综述旨在促进对执行功能跨诊断相关性的理解,并突出未来研究的重要考量因素。我们还讨论了在研究执行功能的跨诊断相关性时同时检查行为和神经标志物的重要性。

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Neuropsychological performance in youth with obsessive-compulsive disorder.青少年强迫症的神经心理学表现。
J Psychiatr Res. 2021 Jun;138:301-310. doi: 10.1016/j.jpsychires.2021.03.066. Epub 2021 Apr 13.
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Effects of Bergen 4-Day Treatment on Resting-State Graph Features in Obsessive-Compulsive Disorder.贝根 4 天治疗对强迫症静息态图特征的影响。
Biol Psychiatry Cogn Neurosci Neuroimaging. 2021 Oct;6(10):973-982. doi: 10.1016/j.bpsc.2020.01.007. Epub 2020 Feb 6.

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