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分析罗马尼亚患者群体发生妊娠期糖尿病的危险因素。

Analysis of Risk Factors for the Development of Gestational Diabetes Mellitus in a Group of Romanian Patients.

机构信息

University of Medicine and Pharmacy of Craiova, Romania.

Clinical County Emergency Hospital of Craiova, Romania.

出版信息

J Diabetes Res. 2022 Jun 2;2022:2367213. doi: 10.1155/2022/2367213. eCollection 2022.

DOI:10.1155/2022/2367213
PMID:35694616
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9184202/
Abstract

INTRODUCTION

Gestational diabetes mellitus (GDM) is caused by numerous risk factors, the most common being old age, obesity, family history of diabetes mellitus, GDM, history of fetal macrosomia, history of polycystic ovary syndrome or treatment with particular drugs, multiple births, and certain races. The study proposed to analyze the risk factors causing GDM.

METHOD

In the study, we included 97 pregnant women to whom there was an OGTT performed between weeks 24th and 28th of pregnancy, divided into two groups, with GDM and without GDM. The statistical analysis was performed with SPSS 26.0, the tests being statistically significant if value < 0.05.

RESULTS

The favoring risk factors for the onset of GDM were analyzed, with statistically significant differences between the GDM group and the group without GDM related to the delivery age (32.39 ± 4.66 years old vs. 28.61 ± 4.71 years old), history of fetal macrosomia (13.7% vs. 0%), presence of GDM during previous pregnancies (7.8% vs. 0%), HBP before pregnancy (9.8% vs. 0%), gestational HBP (17.6% vs. 0%), glycemia value at first medical visit (79.37 ± 9.34 mg/dl vs. 71.39 ± 9.16 mg/dl), and weight gain during pregnancy (14.61 ± 4.47 kg vs. 12.48 ± 5.87 kg).

CONCLUSIONS

Identifying the risk factors for the GDM onset has a special importance, implying an early implementation of interventional measures in order to avoid the onset of GDM and associated maternal and fetal complications.

摘要

简介

妊娠糖尿病(GDM)由多种危险因素引起,最常见的是高龄、肥胖、糖尿病家族史、GDM 史、巨大儿史、多囊卵巢综合征史或特定药物治疗史、多胎妊娠和某些种族。本研究旨在分析导致 GDM 的危险因素。

方法

在这项研究中,我们纳入了 97 名孕妇,她们在妊娠 24 至 28 周之间进行了 OGTT,分为 GDM 组和非 GDM 组。统计分析采用 SPSS 26.0 进行,若 P 值 < 0.05,则认为检验具有统计学意义。

结果

分析了 GDM 发病的危险因素,GDM 组与非 GDM 组在分娩年龄(32.39 ± 4.66 岁比 28.61 ± 4.71 岁)、巨大儿史(13.7%比 0%)、既往妊娠 GDM 史(7.8%比 0%)、妊娠前高血压(9.8%比 0%)、妊娠高血压(17.6%比 0%)、首次就诊时血糖值(79.37 ± 9.34 mg/dl 比 71.39 ± 9.16 mg/dl)和孕期体重增加(14.61 ± 4.47 kg 比 12.48 ± 5.87 kg)方面存在统计学差异。

结论

识别 GDM 发病的危险因素具有特殊意义,这意味着应早期实施干预措施,以避免 GDM 及其相关的母婴并发症的发生。

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本文引用的文献

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Int J Mol Sci. 2021 Sep 30;22(19):10575. doi: 10.3390/ijms221910575.
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Myo-Inositol as a Key Supporter of Fertility and Physiological Gestation.肌醇作为生育能力和生理妊娠的关键支持者。
Pharmaceuticals (Basel). 2021 May 25;14(6):504. doi: 10.3390/ph14060504.
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The Impact of a Plant-Based Diet on Gestational Diabetes: A Review.植物性饮食对妊娠期糖尿病的影响:综述
Antioxidants (Basel). 2021 Apr 2;10(4):557. doi: 10.3390/antiox10040557.
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Mediterranean Diet for the Prevention of Gestational Diabetes in the Covid-19 Era: Implications of Il-6 In Diabesity.新冠疫情时代下的妊娠期糖尿病预防的地中海饮食:肥胖相关 2 型糖尿病中的白细胞介素 6 的意义。
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Lockdown with a Price: The impact of the COVID-19 Pandemic on Prenatal Care and Perinatal Outcomes in a Tertiary Care Center.代价下的封锁:新冠疫情对三级医疗中心产前护理及围产期结局的影响
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