Désiré B, Saint-André S
Experientia. 1987 Apr 15;43(4):395-7. doi: 10.1007/BF01940424.
Cyclodextrins catalyzed the inactivation of sarin and soman but did not inactivate tabun and VX. Furthermore, sarin and soman showed greater affinity for beta-cyclodextrin than for alpha- or gamma-cyclodextrins. Thus beta-cyclodextrin appears to be an attractive starting material for the preparation of a catalyst able to inactivate sarin and soman more effectively. Such a catalyst might contribute to improving the therapy of poisoning caused by these two nerve agents.
环糊精可催化沙林和梭曼失活，但对塔崩和VX无失活作用。此外，沙林和梭曼对β-环糊精的亲和力比对α-或γ-环糊精更高。因此，β-环糊精似乎是制备能更有效地使沙林和梭曼失活的催化剂的有吸引力的起始原料。这样一种催化剂可能有助于改善由这两种神经毒剂引起的中毒的治疗。
