Cancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France.
Radiation Oncology, University of Toronto, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.
Int J Cancer. 2022 Nov 1;151(9):1474-1481. doi: 10.1002/ijc.34163. Epub 2022 Jul 2.
We evaluated the global patterns of non-Hodgkin lymphoma (NHL) in 2020 using the estimates of NHL incidence and mortality in 185 countries that are part of the GLOBOCAN 2020 database, developed by the International Agency for Research on Cancer (IARC). As well as new cases and deaths of NHL, corresponding age-standardized (world) rates (ASR) of incidence and mortality per 100 000 person-years were derived by country and world region. In 2020, an estimated 544 000 new cases of NHL were diagnosed worldwide, and approximately 260 000 people died from the disease. Eastern Asia accounted for a quarter (24.9%) of all cases, followed by Northern America (15.1%) and South-Central Asia (9.7%). Incidence rates were higher in men than in women, with similar geographical patterns. While the incidence rates were highest in Australia and New Zealand, Northern America, Northern Europe and Western Europe (>10/100 000 for both sexes combined), the highest mortality rates (>3/100 000) were found in regions in Africa, Western Asia and Oceania. The large variations and the disproportionately higher mortality in low- and middle-income countries can be related to the underlying prevalence and distribution of risk factors, and to the level of access to diagnostic and treatment facilities.
我们使用国际癌症研究机构（IARC）开发的 GLOBOCAN 2020 数据库中包含的 185 个国家/地区的非霍奇金淋巴瘤（NHL）发病率和死亡率估计值，评估了 2020 年全球 NHL 的流行模式。除 NHL 的新发病例和死亡病例外，还按国家和世界区域计算了相应的年龄标准化（世界）发病率和死亡率（每 10 万人年）。2020 年，全球估计有 544000 例 NHL 新发病例，约有 260000 人死于该病。东亚占所有病例的四分之一（24.9％），其次是北美（15.1％）和南亚中部（9.7％）。男性的发病率高于女性，且具有相似的地理分布模式。虽然澳大利亚和新西兰、北美、北欧和西欧的发病率最高（男女合计均超过 10/100000），但在非洲、西亚和大洋洲的一些地区死亡率最高（>3/100000）。发病率差异较大，中低收入国家的死亡率不成比例地较高，这可能与潜在的危险因素的流行率和分布情况以及获得诊断和治疗设施的水平有关。
