房角镜辅助经巩膜睫状体光凝术治疗葡萄膜炎性青光眼。
Gonioscopy-Assisted Transluminal Trabeculotomy for the Treatment of Glaucoma in Uveitic Eyes.
机构信息
Uveitis Unit, Retina Division, Wills Eye Hospital, Philadelphia, Pennsylvania, USA.
Glaucoma Division, Wills Eye Hospital, Philadelphia, Pennsylvania, USA.
出版信息
Ocul Immunol Inflamm. 2023 Oct;31(8):1608-1614. doi: 10.1080/09273948.2022.2087093. Epub 2022 Jun 13.
PURPOSE
To evaluate the outcomes of gonioscopy-assisted transluminal trabeculotomy (GATT) in adult eyes with uncontrolled uveitic glaucoma.
METHODS
We reviewed 16 eyes from 13 patients. Surgical success was defined as intraocular pressure (IOP) reduction >20% from baseline or IOP between 5 and 21 mmHg by the 3-month visit while on a stable number or fewer IOP-lowering agents and no need for additional glaucoma surgery.
RESULTS
At 12 months, the cumulative success rate was 81%. Mean IOP was 37.8 ± 13.0 mmHg at baseline and 12.2 ± 3.0 mmHg at 12 months (68% reduction; ). The average number of glaucoma medications was 4.6 ± 1.3 at baseline and 2.2 ± 0.7 at 12 months (52% reduction; ). Transient hyphema was seen in 44% of eyes at 1 week.
CONCLUSIONS
This small retrospective study suggests that GATT is effective and safe as an initial surgical treatment for medically refractory glaucoma in uveitic adult eyes.
目的
评估房角镜辅助经巩膜隧道小梁切开术（GATT）治疗成人未控制的葡萄膜炎性青光眼的疗效。
方法
我们回顾了 13 名患者的 16 只眼。手术成功的定义为：在第 3 个月时，眼压（IOP）较基线降低>20%，IOP 为 5 至 21mmHg，同时使用稳定数量或更少的降眼压药物，且无需进一步的青光眼手术。
结果
在 12 个月时，累积成功率为 81%。平均基线 IOP 为 37.8±13.0mmHg，12 个月时为 12.2±3.0mmHg（降低 68%）。平均降眼压药物数在基线时为 4.6±1.3 种，12 个月时为 2.2±0.7 种（降低 52%）。术后 1 周有 44%的眼出现一过性前房积血。
结论
这项小型回顾性研究表明，GATT 作为葡萄膜炎性成人眼药物难治性青光眼的初始手术治疗方法是有效且安全的。
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